Sperm acrosome membrane-associated protein 6 {ECO:0000303|PubMed:24275887}

UniProt data

UniProt name: SACA6_HUMAN (W5XKT8)

Gene name: SPACA6 {ECO:0000312|HGNC:HGNC:27113}; Synonyms=SPACA6P

Organism: Homo sapiens (Human).

Function: Sperm protein potentially involved sperm-egg fusion. {ECO:0000250|UniProtKB:E9Q8Q8}.

Subcellular location: Membrane {ECO:0000255}; Single-pass type I membrane protein {ECO:0000255}.

Transmembrane domains:

  1. 296-316, 21 AA, Helical. {ECO:0000255}.

Sequence: 324 AA

10 20 30 40 50 60 MALLALASAV PSALLALAVF RVPAWACLLC FTTYSERLRI CQMFVGMRSP KLEECEEAFT 70 80 90 100 110 120 AAFQGLSDTE INYDERSHLH DTFTQMTHAL QELAAAQGSF EVAFPDAAEK MKKVITQLKE 130 140 150 160 170 180 AQACIPPCGL QEFARRFLCS GCYSRVCDLP LDCPVQDVTV TRGDQAMFSC IVNFQLPKEE 190 200 210 220 230 240 ITYSWKFAGG GLRTQDLSYF RDMPRAEGYL ARIRPAQLTH RGTFSCVIKQ DQRPLARLYF 250 260 270 280 290 300 FLNVTGPPPR AETELQASFR EVLRWAPRDA ELIEPWRPSL GELLARPEAL TPSNLFLLAV 310 320 LGALASASAT VLAWMFFRWY CSGN

CATM prediction

The sequence of SACA6_HUMAN returned 1 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
         300       310       
  +    |    +    |    +    		 (Å) (°) (Å) (°)  
Model 1 SNLFLLAVLGALASASATVLAWMFFRW 7.3 -44.8° 0.1 45.1 -15.3

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


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Download model 1 structure: PDB, PyMOL session

List of hydrogen bonds:

Donor Acceptor Distance
B, 302, GLY, HA1 A, 299, ALA, O 3.36Å
B, 303, ALA, HA A, 302, GLY, O 3.25Å
B, 306, SER, HG1 A, 303, ALA, O 2.11Å
A, 302, GLY, HA1 B, 299, ALA, O 3.36Å
A, 303, ALA, HA B, 302, GLY, O 3.25Å
A, 306, SER, HG1 B, 303, ALA, O 2.11Å