DnaJ homolog subfamily C member 16

UniProt data

UniProt name: DJC16_HUMAN (Q9Y2G8)

Gene name: DNAJC16; Synonyms=KIAA0962

Organism: Homo sapiens (Human).

Function:

Subcellular location: Membrane {ECO:0000305}; Single-pass type IV membrane protein {ECO:0000305}.

Transmembrane domains:

  1. 536-556, 21 AA, Helical; Anchor for type IV membrane protein. {ECO:0000255}.

Sequence: 782 AA

10 20 30 40 50 60 MEVRKLSISW QFLIVLVLIL QILSALDFDP YRVLGVSRTA SQADIKKAYK KLAREWHPDK 70 80 90 100 110 120 NKDPGAEDKF IQISKAYEIL SNEEKRSNYD QYGDAGENQG YQKQQQQREY RFRHFHENFY 130 140 150 160 170 180 FDESFFHFPF NSERRDSIDE KYLLHFSHYV NEVVPDSFKK PYLIKITSDW CFSCIHIEPV 190 200 210 220 230 240 WKEVIQELEE LGVGIGVVHA GYERRLAHHL GAHSTPSILG IINGKISFFH NAVVRENLRQ 250 260 270 280 290 300 FVESLLPGNL VEKVTNKNYV RFLSGWQQEN KPHVLLFDQT PIVPLLYKLT AFAYKDYLSF 310 320 330 340 350 360 GYVYVGLRGT EEMTRRYNIN IYAPTLLVFK EHINRPADVI QARGMKKQII DDFITRNKYL 370 380 390 400 410 420 LAARLTSQKL FHELCPVKRS HRQRKYCVVL LTAETTKLSK PFEAFLSFAL ANTQDTVRFV 430 440 450 460 470 480 HVYSNRQQEF ADTLLPDSEA FQGKSAVSIL ERRNTAGRVV YKTLEDPWIG SESDKFILLG 490 500 510 520 530 540 YLDQLRKDPA LLSSEAVLPD LTDELAPVFL LRWFYSASDY ISDCWDSIFH NNWREMMPLL 550 560 570 580 590 600 SLIFSALFIL FGTVIVQAFS DSNDERESSP PEKEEAQEKT GKTEPSFTKE NSSKIPKKGF 610 620 630 640 650 660 VEVTELTDVT YTSNLVRLRP GHMNVVLILS NSTKTSLLQK FALEVYTFTG SSCLHFSFLS 670 680 690 700 710 720 LDKHREWLEY LLEFAQDAAP IPNQYDKHFM ERDYTGYVLA LNGHKKYFCL FKPQKTVEEE 730 740 750 760 770 780 EAIGSCSDVD SSLYLGESRG KPSCGLGSRP IKGKLSKLSL WMERLLEGSL QRFYIPSWPE LD

CATM prediction

The sequence of DJC16_HUMAN returned 1 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
         540       550       
  +    |    +    |    +    		 (Å) (°) (Å) (°)  
Model 1 WREMMALLSLIFSALFILFGTVIVQAF 7.4 -50.0° 2.8 47.0 -12.9
Prolines* WREMMPLLSLIFSALFILFGTVIVQAF          

* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


Click on the image to enlarge

Download model 1 structure: PDB, PyMOL session

List of hydrogen bonds:

Donor Acceptor Distance
B, 549, ILE, HA A, 548, PHE, O 3.42Å
B, 552, GLY, HA1 A, 549, ILE, O 3.37Å
A, 549, ILE, HA B, 548, PHE, O 3.42Å
A, 552, GLY, HA1 B, 549, ILE, O 3.37Å