RING finger protein 24

UniProt data

UniProt name: RNF24_HUMAN (Q9Y225)

Gene name: RNF24

Organism: Homo sapiens (Human).

Function: May play a role in TRPCs intracellular trafficking. {ECO:0000269|PubMed:17850865}.

Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:17850865}; Single-pass membrane protein {ECO:0000269|PubMed:17850865}.

Transmembrane domains:

  1. 24-44, 21 AA, Helical. {ECO:0000255}.

Sequence: 148 AA

10 20 30 40 50 60 MSSDFPHYNF RMPNIGFQNL PLNIYIVVFG TAIFVFILSL LFCCYLIRLR HQAHKEFYAY 70 80 90 100 110 120 KQVILKEKVK ELNLHELCAV CLEDFKPRDE LGICPCKHAF HRKCLIKWLE VRKVCPLCNM 130 140 PVLQLAQLHS KQDRGPPQGP LPGAENIV

CATM prediction

The sequence of RNF24_HUMAN returned 1 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
           30        40      
    +    |    +    |    +  		 (Å) (°) (Å) (°)  
Model 1 ALNIYIVVFGTAIFVFILSLLFCCYLI 7.3 -55.0° 2.4 47.9 -1.5
Prolines* PLNIYIVVFGTAIFVFILSLLFCCYLI          

* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


Click on the image to enlarge

Download model 1 structure: PDB, PyMOL session

List of hydrogen bonds:

Donor Acceptor Distance
B, 27, VAL, HA A, 26, ILE, O 3.47Å
B, 30, GLY, HA1 A, 27, VAL, O 3.23Å
A, 27, VAL, HA B, 26, ILE, O 3.47Å
A, 30, GLY, HA1 B, 27, VAL, O 3.23Å