Protocadherin gamma-C3

UniProt data

UniProt name: PCDGK_HUMAN (Q9UN70)

Gene name: PCDHGC3; Synonyms=PCDH2

Organism: Homo sapiens (Human).

Function: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

Subcellular location: Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.

Transmembrane domains:

  1. 694-714, 21 AA, Helical. {ECO:0000255}.

Sequence: 934 AA

10 20 30 40 50 60 MVPEAWRSGL VSTGRVVGVL LLLGALNKAS TVIHYEIPEE REKGFAVGNV VANLGLDLGS 70 80 90 100 110 120 LSARRFRVVS GASRRFFEVN RETGEMFVND RLDREELCGT LPSCTVTLEL VVENPLELFS 130 140 150 160 170 180 VEVVIQDIND NNPAFPTQEM KLEISEAVAP GTRFPLESAH DPDVGSNSLQ TYELSRNEYF 190 200 210 220 230 240 ALRVQTREDS TKYAELVLER ALDREREPSL QLVLTALDGG TPALSASLPI HIKVLDANDN 250 260 270 280 290 300 APVFNQSLYR ARVLEDAPSG TRVVQVLATD LDEGPNGEII YSFGSHNRAG VRQLFALDLV 310 320 330 340 350 360 TGMLTIKGRL DFEDTKLHEI YIQAKDKGAN PEGAHCKVLV EVVDVNDNAP EITVTSVYSP 370 380 390 400 410 420 VPEDAPLGTV IALLSVTDLD AGENGLVTCE VPPGLPFSLT SSLKNYFTLK TSADLDRETV 430 440 450 460 470 480 PEYNLSITAR DAGTPSLSAL TIVRVQVSDI NDNPPQSSQS SYDVYIEENN LPGAPILNLS 490 500 510 520 530 540 VWDPDAPQNA RLSFFLLEQG AETGLVGRYF TINRDNGIVS SLVPLDYEDR REFELTAHIS 550 560 570 580 590 600 DGGTPVLATN ISVNIFVTDR NDNAPQVLYP RPGGSSVEML PRGTSAGHLV SRVVGWDADA 610 620 630 640 650 660 GHNAWLSYSL LGSPNQSLFA IGLHTGQIST ARPVQDTDSP RQTLTVLIKD NGEPSLSTTA 670 680 690 700 710 720 TLTVSVTEDS PEARAEFPSG SAPREQKKNL TFYLLLSLIL VSVGFVVTVF GVIIFKVYKW 730 740 750 760 770 780 KQSRDLYRAP VSSLYRTPGP SLHADAVRGG LMSPHLYHQV YLTTDSRRSD PLLKKPGAAS 790 800 810 820 830 840 PLASRQNTLR SCDPVFYRQV LGAESAPPGQ QAPPNTDWRF SQAQRPGTSG SQNGDDTGTW 850 860 870 880 890 900 PNNQFDTEML QAMILASASE AADGSSTLGG GAGTMGLSAR YGPQFTLQHV PDYRQNVYIP 910 920 930 GSNATLTNAA GKRDGKAPAG GNGNKKKSGK KEKK

CATM prediction

The sequence of PCDGK_HUMAN returned 1 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
           700       710     
    +    |    +    |    +  		 (Å) (°) (Å) (°)  
Model 1 TFYLLLSLILVSVGFVVTVFGVIIFKV 7.4 -47.0° 2.3 44.7 -24.4

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


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Download model 1 structure: PDB, PyMOL session

List of hydrogen bonds:

Donor Acceptor Distance
B, 704, GLY, HA1 A, 701, VAL, O 3.50Å
B, 705, PHE, HA A, 708, THR, OG1 2.42Å
A, 704, GLY, HA1 B, 701, VAL, O 3.50Å
A, 705, PHE, HA B, 708, THR, OG1 2.42Å