Cadherin-7

UniProt data

UniProt name: CADH7_HUMAN (Q9ULB5)

Gene name: CDH7; Synonyms=CDH7L1

Organism: Homo sapiens (Human).

Function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

Subcellular location: Cell membrane; Single-pass type I membrane protein.

Transmembrane domains:

  1. 608-628, 21 AA, Helical. {ECO:0000255}.

Sequence: 785 AA

10 20 30 40 50 60 MKLGKVEFCH FLQLIALFLC FSGMSQAELS RSRSKPYFQS GRSRTKRSWV WNQFFVLEEY 70 80 90 100 110 120 MGSDPLYVGK LHSDVDKGDG SIKYILSGEG ASSIFIIDEN TGDIHATKRL DREEQAYYTL 130 140 150 160 170 180 RAQALDRLTN KPVEPESEFV IKIQDINDNE PKFLDGPYTA GVPEMSPVGT SVVQVTATDA 190 200 210 220 230 240 DDPTYGNSAR VVYSILQGQP YFSVEPKTGV IKTALPNMDR EAKDQYLLVI QAKDMVGQNG 250 260 270 280 290 300 GLSGTTSVTV TLTDVNDNPP RFPRRSYQYN VPESLPVASV VARIKAADAD IGANAEMEYK 310 320 330 340 350 360 IVDGDGLGIF KISVDKETQE GIITIQKELD FEAKTSYTLR IEAANKDADP RFLSLGPFSD 370 380 390 400 410 420 TTTVKIIVED VDEPPVFSSP LYPMEVSEAT QVGNIIGTVA AHDPDSSNSP VRYSIDRNTD 430 440 450 460 470 480 LERYFNIDAN SGVITTAKSL DRETNAIHNI TVLAMESQNP SQVGRGYVAI TILDINDNAP 490 500 510 520 530 540 EFAMDYETTV CENAQPGQVI QKISAVDKDE PSNGHQFYFS LTTDATNNHN FSLKDNKDNT 550 560 570 580 590 600 ASILTRRNGF RRQEQSVYYL PIFIVDSGSP SLSSTNTLTI RVCDCDADGV AQTCNAEAYV 610 620 630 640 650 660 LPAGLSTGAL IAILACVLTL LVLILLIVTM RRRKKEPLIF DEERDIRENI VRYDDEGGGE 670 680 690 700 710 720 EDTEAFDMAA LRNLNVIRDT KTRRDVTPEI QFLSRPAFKS IPDNVIFREF IWERLKEADV 730 740 750 760 770 780 DPGAPPYDSL QTYAFEGNGS VAESLSSLDS ISSNSDQNYD YLSDWGPRFK RLADMYGTGQ ESLYS

CATM prediction

The sequence of CADH7_HUMAN returned 1 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
       610       620       63
+    |    +    |    +    | 		 (Å) (°) (Å) (°)  
Model 1 LSTGALIAILACVLTLLVLILLIVTMR 7.3 -47.0° 6.0 45.0 -8.0

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


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Download model 1 structure: PDB, PyMOL session

List of hydrogen bonds:

Donor Acceptor Distance
B, 609, ALA, HA A, 608, GLY, O 3.25Å
A, 609, ALA, HA B, 608, GLY, O 3.25Å