Retinoic acid receptor responder protein 3

UniProt data

UniProt name: HRSL4_HUMAN (Q9UL19)

Gene name: RARRES3; Synonyms=RIG1, TIG3

Organism: Homo sapiens (Human).

Function: Exhibits PLA1/2 activity, catalyzing the calcium- independent hydrolysis of acyl groups in various phosphotidylcholines (PC) and phosphatidylethanolamine (PE). For most substrates, PLA1 activity is much higher than PLA2 activity. N- and O-acylation activity is hardly detectable. {ECO:0000269|PubMed:19615464}.

Subcellular location: Membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}.

Transmembrane domains:

  1. 134-155, 22 AA, Helical. {ECO:0000255}.

Sequence: 164 AA

10 20 30 40 50 60 MASPHQEPKP GDLIEIFRLG YEHWALYIGD GYVIHLAPPS EYPGAGSSSV FSVLSNSAEV 70 80 90 100 110 120 KRERLEDVVG GCCYRVNNSL DHEYQPRPVE VIISSAKEMV GQKMKYSIVS RNCEHFVTQL 130 140 150 160 RYGKSRCKQV EKAKVEVGVA TALGILVVAG CSFAIRRYQK KATA

CATM prediction

The sequence of HRSL4_HUMAN returned 1 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
           140       150      
    +    |    +    |    +   		 (Å) (°) (Å) (°)  
Model 1 EKAKVEVGVATALGILVVAGCSFAIRRY 7.4 -50.8° 3.3 48.0 -1.4

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


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Download model 1 structure: PDB, PyMOL session

List of hydrogen bonds:

Donor Acceptor Distance
B, 141, THR, HA A, 140, ALA, O 3.36Å
B, 144, GLY, HA1 A, 141, THR, O 3.46Å
A, 141, THR, HA B, 140, ALA, O 3.36Å
A, 144, GLY, HA1 B, 141, THR, O 3.46Å