UniProt data
UniProt name: CLC1B_HUMAN (Q9P126)
Gene name: CLEC1B; Synonyms=CLEC2; ORFNames=UNQ721/PRO1384
Organism: Homo sapiens (Human).
Function:
Subcellular location: Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Transmembrane domains:
- 34-54, 21 AA, Helical; Signal-anchor for type II membrane protein. {ECO:0000255}.
Sequence: 229 AA
10 20 30 40 50 60
MQDEDGYITL NIKTRKPALI SVGSASSSWW RVMALILLIL CVGMVVGLVA LGIWSVMQRN
70 80 90 100 110 120
YLQGENENRT GTLQQLAKRF CQYVVKQSEL KGTFKGHKCS PCDTNWRYYG DSCYGFFRHN
130 140 150 160 170 180
LTWEESKQYC TDMNATLLKI DNRNIVEYIK ARTHLIRWVG LSRQKSNEVW KWEDGSVISE
190 200 210 220
NMFEFLEDGK GNMNCAYFHN GKMHPTFCEN KHYLMCERKA GMTKVDQLP
CATM prediction
The sequence of CLC1B_HUMAN returned 2 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 40 50 + | + | + |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | RVMALILLILCVGMVVGLVALGIWSVM | 6.6 | -55.1° | 5.8 | 47.0 | -25.1 |
| Model 2 | RVMALILLILCVGMVVGLVALGIWSVM | 7.0 | +53.8° | 3.3 | 79.8 | -12.3 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 43, GLY, HA1 | A, 40, LEU, O | 3.03Å |
| B, 44, MET, HA | A, 43, GLY, O | 2.63Å |
| B, 47, GLY, HA1 | A, 44, MET, O | 3.41Å |
| A, 43, GLY, HA1 | B, 40, LEU, O | 3.03Å |
| A, 44, MET, HA | B, 43, GLY, O | 2.63Å |
| A, 47, GLY, HA1 | B, 44, MET, O | 3.41Å |
