Glycoprotein integral membrane protein 1

UniProt data

UniProt name: GINM1_HUMAN (Q9NU53)

Gene name: GINM1; Synonyms=C6orf72; ORFNames=UNQ710/PRO1361

Organism: Homo sapiens (Human).

Function:

Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.

Transmembrane domains:

  1. 269-289, 21 AA, Helical. {ECO:0000255}.

Sequence: 330 AA

10 20 30 40 50 60 MEGAPPGSLA LRLLLFVALP ASGWLTTGAP EPPPLSGAPQ DGIRINVTTL KDDGDISKQQ 70 80 90 100 110 120 VVLNITYESG QVYVNDLPVN SGVTRISCQT LIVKNENLEN LEEKEYFGIV SVRILVHEWP 130 140 150 160 170 180 MTSGSSLQLI VIQEEVVEID GKQVQQKDVT EIDILVKNRG VLRHSNYTLP LEESMLYSIS 190 200 210 220 230 240 RDSDILFTLP NLSKKESVSS LQTTSQYLIR NVETTVDEDV LPGKLPETPL RAEPPSSYKV 250 260 270 280 290 300 MCQWMEKFRK DLCRFWSNVF PVFFQFLNIM VVGITGAAVV ITILKVFFPV SEYKGILQLD 310 320 KVDVIPVTAI NLYPDGPEKR AENLEDKTCI

CATM prediction

The sequence of GINM1_HUMAN returned 2 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
      270       280       290
    |    +    |    +    |  		 (Å) (°) (Å) (°)  
Model 1 FLNIMVVGITGAAVVITILKVFFAVSE 7.2 -47.0° 1.3 45.2 -15.2
Model 2 FLNIMVVGITGAAVVITILKVFFAVSE 7.3 -51.1° 2.4 45.2 -4.2
Prolines* FLNIMVVGITGAAVVITILKVFFPVSE          

* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


Click on the image to enlarge

Download model 1 structure: PDB, PyMOL session

List of hydrogen bonds:

Donor Acceptor Distance
B, 273, GLY, HA1 A, 270, MET, O 3.16Å
B, 274, ILE, HA A, 273, GLY, O 3.36Å
A, 273, GLY, HA1 B, 270, MET, O 3.16Å
A, 274, ILE, HA B, 273, GLY, O 3.36Å