UniProt data
UniProt name: MANBL_HUMAN (Q9NQG1)
Gene name: MANBAL
Organism: Homo sapiens (Human).
Function:
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Transmembrane domains:
- 24-44, 21 AA, Helical. {ECO:0000255}.
Sequence: 85 AA
10 20 30 40 50 60
MASDLDFSPP EVPEPTFLEN LLRYGLFLGA IFQLICVLAI IVPIPKSHEA EAEPSEPRSA
70 80
EVTRKPKAAV PSVNKRPKKE TKKKR
CATM prediction
The sequence of MANBL_HUMAN returned 4 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 30 40 + | + | + |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | LLRYGLFLGAIFQLICVLAIIVAIAKS | 7.2 | -25.0° | 2.7 | 52.0 | -31.2 |
| Model 2 | LLRYGLFLGAIFQLICVLAIIVAIAKS | 6.9 | -43.7° | 1.8 | 45.3 | -30.3 |
| Model 3 | LLRYGLFLGAIFQLICVLAIIVAIAKS | 7.3 | -40.0° | 4.1 | 37.7 | -23.8 |
| Model 4 | LLRYGLFLGAIFQLICVLAIIVAIAKS | 6.7 | -55.0° | 0.9 | 50.0 | -6.2 |
| Prolines* | LLRYGLFLGAIFQLICVLAIIVPIPKS |
* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 33, GLN, HA | A, 33, GLN, OE1 | 2.73Å |
| A, 33, GLN, HA | B, 33, GLN, OE1 | 2.73Å |
