UniProt data
UniProt name: PCD18_HUMAN (Q9HCL0)
Gene name: PCDH18; Synonyms=KIAA1562
Organism: Homo sapiens (Human).
Function: Potential calcium-dependent cell-adhesion protein.
Subcellular location: Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Transmembrane domains:
- 700-720, 21 AA, Helical. {ECO:0000255}.
Sequence: 1135 AA
10 20 30 40 50 60
MHQMNAKMHF RFVFALLIVS FNHDVLGKNL KYRIYEEQRV GSVIARLSED VADVLLKLPN
70 80 90 100 110 120
PSTVRFRAMQ RGNSPLLVVN EDNGEISIGA TIDREQLCQK NLNCSIEFDV ITLPTEHLQL
130 140 150 160 170 180
FHIEVEVLDI NDNSPQFSRS LIPIEISESA AVGTRIPLDS AFDPDVGENS LHTYSLSAND
190 200 210 220 230 240
FFNIEVRTRT DGAKYAELIV VRELDRELKS SYELQLTASD MGVPQRSGSS ILKISISDSN
250 260 270 280 290 300
DNSPAFEQQS YIIQLLENSP VGTLLLDLNA TDPDEGANGK IVYSFSSHVS PKIMETFKID
310 320 330 340 350 360
SERGHLTLFK QVDYEITKSY EIDVQAQDLG PNSIPAHCKI IIKVVDVNDN KPEININLMS
370 380 390 400 410 420
PGKEEISYIF EGDPIDTFVA LVRVQDKDSG LNGEIVCKLH GHGHFKLQKT YENNYLILTN
430 440 450 460 470 480
ATLDREKRSE YSLTVIAEDR GTPSLSTVKH FTVQINDIND NPPHFQRSRY EFVISENNSP
490 500 510 520 530 540
GAYITTVTAT DPDLGENGQV TYTILESFIL GSSITTYVTI DPSNGAIYAL RIFDHEEVSQ
550 560 570 580 590 600
ITFVVEARDG GSPKQLVSNT TVVLTIIDEN DNVPVVIGPA LRNNTAEITI PKGAESGFHV
610 620 630 640 650 660
TRIRAIDRDS GVNAELSCAI VAGNEENIFI IDPRSCDIHT NVSMDSVPYT EWELSVIIQD
670 680 690 700 710 720
KGNPQLHTKV LLKCMIFEYA ESVTSTAMTS VSQASLDVSM IIIISLGAIC AVLLVIMVLF
730 740 750 760 770 780
ATRCNREKKD TRSYNCRVAE STYQHHPKRP SRQIHKGDIT LVPTINGTLP IRSHHRSSPS
790 800 810 820 830 840
SSPTLERGQM GSRQSHNSHQ SLNSLVTISS NHVPENFSLE LTHATPAVEQ VSQLLSMLHQ
850 860 870 880 890 900
GQYQPRPSFR GNKYSRSYRY ALQDMDKFSL KDSGRGDSEA GDSDYDLGRD SPIDRLLGEG
910 920 930 940 950 960
FSDLFLTDGR IPAAMRLCTE ECRVLGHSDQ CWMPPLPSPS SDYRSNMFIP GEEFPTQPQQ
970 980 990 1000 1010 1020
QHPHQSLEDD AQPADSGEKK KSFSTFGKDS PNDEDTGDTS TSSLLSEMSS VFQRLLPPSL
1030 1040 1050 1060 1070 1080
DTYSECSEVD RSNSLERRKG PLPAKTVGYP QGVAAWAAST HFQNPTTNCG PPLGTHSSVQ
1090 1100 1110 1120 1130
PSSKWLPAME EIPENYEEDD FDNVLNHLND GKHELMDASE LVAEINKLLQ DVRQS
CATM prediction
The sequence of PCD18_HUMAN returned 1 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 700 710 720 | + | + | |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | DVSMIIIISLGAICAVLLVIMVLFATR | 7.1 | -52.0° | 0.6 | 48.1 | -18.8 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 707, GLY, HA1 | A, 704, ILE, O | 3.16Å |
| B, 708, ALA, HA | A, 707, GLY, O | 3.21Å |
| A, 707, GLY, HA1 | B, 704, ILE, O | 3.16Å |
| A, 708, ALA, HA | B, 707, GLY, O | 3.21Å |