UniProt data
UniProt name: PCDH9_HUMAN (Q9HC56)
Gene name: PCDH9
Organism: Homo sapiens (Human).
Function: Potential calcium-dependent cell-adhesion protein.
Subcellular location: Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Transmembrane domains:
- 815-835, 21 AA, Helical. {ECO:0000255}.
Sequence: 1237 AA
10 20 30 40 50 60
MDLRDFYLLA ALIACLRLDS AIAQELIYTI REELPENVPI GNIPKDLNIS HINAATGTSA
70 80 90 100 110 120
SLVYRLVSKA GDAPLVKVSS STGEIFTTSN RIDREKLCAG ASYAEENECF FELEVVILPN
130 140 150 160 170 180
DFFRLIKIKI IVKDTNDNAP MFPSPVINIS IPENTLINSR FPIPSATDPD TGFNGVQHYE
190 200 210 220 230 240
LLNGQSVFGL DIVETPEGEK WPQLIVQQNL DREQKDTYVM KIKVEDGGTP QKSSTAILQV
250 260 270 280 290 300
TVSDVNDNRP VFKEGQVEVH IPENAPVGTS VIQLHATDAD IGSNAEIRYI FGAQVAPATK
310 320 330 340 350 360
RLFALNNTTG LITVQRSLDR EETAIHKVTV LASDGSSTPA RATVTINVTD VNDNPPNIDL
370 380 390 400 410 420
RYIISPINGT VYLSEKDPVN TKIALITVSD KDTDVNGKVI CFIEREVPFH LKAVYDNQYL
430 440 450 460 470 480
LETSSLLDYE GTKEFSFKIV ASDSGKPSLN QTALVRVKLE DENDNPPIFN QPVIELSVSE
490 500 510 520 530 540
NNRRGLYLTT ISATDEDSGK NADIVYQLGP NASFFDLDRK TGVLTASRVF DREEQERFIF
550 560 570 580 590 600
TVTARDNGTP PLQSQAAVIV TVLDENDNSP KFTHNHFQFF VSENLPKYST VGVITVTDAD
610 620 630 640 650 660
AGENKAVTLS ILNDNDNFVL DPYSGVIKSN VSFDREQQSS YTFDVKATDG GQPPRSSTAK
670 680 690 700 710 720
VTINVMDVND NSPVVISPPS NTSFKLVPLS AIPGSVVAEV FAVDVDTGMN AELKYTIVSG
730 740 750 760 770 780
NNKGLFRIDP VTGNITLEEK PAPTDVGLHR LVVNISDLGY PKSLHTLVLV FLYVNDTAGN
790 800 810 820 830 840
ASYIYDLIRR TMETPLDRNI GDSSQPYQNE DYLTIMIAII AGAMVVIVVI FVTVLVRCRH
850 860 870 880 890 900
ASRFKAAQRS KQGAEWMSPN QENKQNKKKK RKKRKSPKSS LLNFVTIEES KPDDAVHEPI
910 920 930 940 950 960
NGTISLPAEL EEQSIGRFDW GPAPPTTFKP NSPDLAKHYK SASPQPAFHL KPDTPVSVKK
970 980 990 1000 1010 1020
HHVIQELPLD NTFVGGCDTL SKRSSTSSDH FSASECSSQG GFKTKGPLHT RQCNSHSKSD
1030 1040 1050 1060 1070 1080
NIPVTPQKCP SSTGFHIQEN EESHYESQRR VTFHLPDGSQ ESCSDSGLGD HEPVGSGTLI
1090 1100 1110 1120 1130 1140
SHPLPLVQPQ DEFYDQASPD KRTEADGNSD PNSDGPLGPR GLAEATEMCT QECLVLGHSD
1150 1160 1170 1180 1190 1200
NCWMPPGLGP YQHPKSPLST FAPQKEWVKK DKLVNGHTLT RAWKEDSNRN QFNDRKQYGS
1210 1220 1230
NEGHFNNGSH MTDIPLANLK SYKQAGGATE SPKEHQL
CATM prediction
The sequence of PCDH9_HUMAN returned 1 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 820 830 + | + | + |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | YLTIMIAIIAGAMVVIVVIFVTVLVRC | 7.2 | -53.7° | 2.9 | 50.8 | -30.5 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 819, ILE, HA | A, 818, ALA, O | 3.15Å |
| B, 822, GLY, HA1 | A, 819, ILE, O | 3.09Å |
| A, 819, ILE, HA | B, 818, ALA, O | 3.15Å |
| A, 822, GLY, HA1 | B, 819, ILE, O | 3.09Å |