Collectrin

UniProt data

UniProt name: TMM27_HUMAN (Q9HBJ8)

Gene name: TMEM27; ORFNames=UNQ679/PRO1312

Organism: Homo sapiens (Human).

Function: Regulator of SNARE complex function. Stimulator of beta cell replication. {ECO:0000269|PubMed:16330323}.

Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.

Transmembrane domains:

  1. 142-162, 21 AA, Helical. {ECO:0000255}.

Sequence: 222 AA

10 20 30 40 50 60 MLWLLFFLVT AIHAELCQPG AENAFKVRLS IRTALGDKAY AWDTNEEYLF KAMVAFSMRK 70 80 90 100 110 120 VPNREATEIS HVLLCNVTQR VSFWFVVTDP SKNHTLPAVE VQSAIRMNKN RINNAFFLND 130 140 150 160 170 180 QTLEFLKIPS TLAPPMDPSV PIWIIIFGVI FCIIIVAIAL LILSGIWQRR RKNKEPSEVD 190 200 210 220 DAEDKCENMI TIENGIPSDP LDMKGGHIND AFMTEDERLT PL

CATM prediction

The sequence of TMM27_HUMAN returned 1 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
   140       150       160   
 |    +    |    +    |    +		 (Å) (°) (Å) (°)  
Model 1 SVAIWIIIFGVIFCIIIVAIALLILSG 7.3 -55.0° 2.4 48.0 -7.1
Prolines* SVPIWIIIFGVIFCIIIVAIALLILSG          

* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


Click on the image to enlarge

Download model 1 structure: PDB, PyMOL session

List of hydrogen bonds:

Donor Acceptor Distance
B, 145, ILE, HA A, 144, ILE, O 3.49Å
B, 148, GLY, HA1 A, 145, ILE, O 3.24Å
A, 145, ILE, HA B, 144, ILE, O 3.49Å
A, 148, GLY, HA1 B, 145, ILE, O 3.24Å