RING finger protein 122

UniProt data

UniProt name: RN122_HUMAN (Q9H9V4)

Gene name: RNF122

Organism: Homo sapiens (Human).

Function: May induce necrosis and apoptosis. May play a role in cell viability. {ECO:0000269|PubMed:16751333}.

Subcellular location: Golgi apparatus {ECO:0000269|PubMed:16778963}. Endoplasmic reticulum {ECO:0000269|PubMed:16778963}. Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.

Transmembrane domains:

  1. 40-60, 21 AA, Helical. {ECO:0000255}.

Sequence: 155 AA

10 20 30 40 50 60 MHPFQWCNGC FCGLGLVSTN KSCSMPPISF QDLPLNIYMV IFGTGIFVFM LSLIFCCYFI 70 80 90 100 110 120 SKLRNQAQSE RYGYKEVVLK GDAKKLQLYG QTCAVCLEDF KGKDELGVLP CQHAFHRKCL 130 140 150 VKWLEVRCVC PMCNKPIASP SEATQNIGIL LDELV

CATM prediction

The sequence of RN122_HUMAN returned 1 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
     40        50        60  
   |    +    |    +    |   		 (Å) (°) (Å) (°)  
Model 1 IYMVIFGTGIFVFMLSLIFCCYFISKL 7.3 -55.0° 2.4 48.0 -2.3

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


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Download model 1 structure: PDB, PyMOL session

List of hydrogen bonds:

Donor Acceptor Distance
B, 43, GLY, HA1 A, 40, VAL, O 3.23Å
A, 43, GLY, HA1 B, 40, VAL, O 3.23Å