UniProt data
UniProt name: CA115_HUMAN (Q9H7X2)
Gene name: C1orf115
Organism: Homo sapiens (Human).
Function:
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Transmembrane domains:
- 116-138, 23 AA, Helical. {ECO:0000255}.
Sequence: 142 AA
10 20 30 40 50 60
MTVGARLRSK AESSLLRRGP RGRGRTEGDE EAAAILEHLE YADEAEAAAE SGTSAADERG
70 80 90 100 110 120
PGTRGARRVH FALLPERYEP LEEPAPSEQP RKRYRRKLKK YGKNVGKVII KGCRYVVIGL
130 140
QGFAAAYSAP FAVATSVVSF VR
CATM prediction
The sequence of CA115_HUMAN returned 2 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 120 130 14 + | + | + | |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | CRYVVIGLQGFAAAYSAAFAVATSVVSFV | 7.2 | -42.0° | 1.4 | 44.8 | -12.6 |
| Model 2 | CRYVVIGLQGFAAAYSAAFAVATSVVSFV | 7.3 | -54.0° | 3.6 | 49.0 | -2.6 |
| Prolines* | CRYVVIGLQGFAAAYSAPFAVATSVVSFV |
* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 119, GLY, HA2 | A, 118, ILE, O | 3.50Å |
| B, 122, GLY, HA1 | A, 119, GLY, O | 3.25Å |
| B, 123, PHE, HA | A, 122, GLY, O | 3.39Å |
| A, 119, GLY, HA2 | B, 118, ILE, O | 3.50Å |
| A, 122, GLY, HA1 | B, 119, GLY, O | 3.25Å |
| A, 123, PHE, HA | B, 122, GLY, O | 3.39Å |
