UniProt data
UniProt name: TNMD_HUMAN (Q9H2S6)
Gene name: TNMD; Synonyms=CHM1L; ORFNames=UNQ771/PRO1565
Organism: Homo sapiens (Human).
Function: May be an angiogenesis inhibitor.
Subcellular location: Isoform 3: Cytoplasm.
Transmembrane domains:
- 31-50, 20 AA, Helical; Signal-anchor for type II membrane protein. {ECO:0000255}.
Sequence: 317 AA
10 20 30 40 50 60
MAKNPPENCE DCHILNAEAF KSKKICKSLK ICGLVFGILA LTLIVLFWGS KHFWPEVPKK
70 80 90 100 110 120
AYDMEHTFYS NGEKKKIYME IDPVTRTEIF RSGNGTDETL EVHDFKNGYT GIYFVGLQKC
130 140 150 160 170 180
FIKTQIKVIP EFSEPEEEID ENEEITTTFF EQSVIWVPAE KPIENRDFLK NSKILEICDN
190 200 210 220 230 240
VTMYWINPTL ISVSELQDFE EEGEDLHFPA NEKKGIEQNE QWVVPQVKVE KTRHARQASE
250 260 270 280 290 300
EELPINDYTE NGIEFDPMLD ERGYCCIYCR RGNRYCRRVC EPLLGYYPYP YCYQGGRVIC
310
RVIMPCNWWV ARMLGRV
CATM prediction
The sequence of TNMD_HUMAN returned 2 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 30 40 50 | + | + | |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | SLKICGLVFGILALTLIVLFWGSKHF | 7.3 | -30.0° | 4.7 | 39.0 | -3.2 |
| Model 2 | SLKICGLVFGILALTLIVLFWGSKHF | 7.0 | +54.1° | 3.3 | 80.2 | -2.9 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
