UniProt data
UniProt name: TMX4_HUMAN (Q9H1E5)
Gene name: TMX4; Synonyms=KIAA1162, TXNDC13
Organism: Homo sapiens (Human).
Function:
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Transmembrane domains:
- 190-210, 21 AA, Helical. {ECO:0000255}.
Sequence: 349 AA
10 20 30 40 50 60
MAGGRCGPQL TALLAAWIAA VAATAGPEEA ALPPEQSRVQ PMTASNWTLV MEGEWMLKFY
70 80 90 100 110 120
APWCPSCQQT DSEWEAFAKN GEILQISVGK VDVIQEPGLS GRFFVTTLPA FFHAKDGIFR
130 140 150 160 170 180
RYRGPGIFED LQNYILEKKW QSVEPLTGWK SPASLTMSGM AGLFSISGKI WHLHNYFTVT
190 200 210 220 230 240
LGIPAWCSYV FFVIATLVFG LFMGLVLVVI SECFYVPLPR HLSERSEQNR RSEEAHRAEQ
250 260 270 280 290 300
LQDAEEEKDD SNEEENKDSL VDDEEEKEDL GDEDEAEEEE EEDNLAAGVD EERSEANDQG
310 320 330 340
PPGEDGVTRE EVEPEEAEEG ISEQPCPADT EVVEDSLRQR KSQHADKGL
CATM prediction
The sequence of TMX4_HUMAN returned 1 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 190 200 210 | + | + | |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | CSYVFFVIATLVFGLFMGLVLVVISEC | 6.6 | -48.1° | 0.7 | 54.0 | -36.1 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 197, LEU, HA | A, 196, THR, O | 3.24Å |
| B, 200, GLY, HA1 | A, 197, LEU, O | 2.79Å |
| B, 201, LEU, HA | A, 200, GLY, O | 2.77Å |
| A, 197, LEU, HA | B, 196, THR, O | 3.24Å |
| A, 200, GLY, HA1 | B, 197, LEU, O | 2.79Å |
| A, 201, LEU, HA | B, 200, GLY, O | 2.77Å |