UniProt data
UniProt name: SLIK2_HUMAN (Q9H156)
Gene name: SLITRK2; Synonyms=CXorf2, KIAA1854, SLITL1
Organism: Homo sapiens (Human).
Function: Suppresses neurite outgrowth. {ECO:0000250|UniProtKB:Q810C0}.
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Transmembrane domains:
- 622-642, 21 AA, Helical. {ECO:0000255}.
Sequence: 845 AA
10 20 30 40 50 60
MLSGVWFLSV LTVAGILQTE SRKTAKDICK IRCLCEEKEN VLNINCENKG FTTVSLLQPP
70 80 90 100 110 120
QYRIYQLFLN GNLLTRLYPN EFVNYSNAVT LHLGNNGLQE IRTGAFSGLK TLKRLHLNNN
130 140 150 160 170 180
KLEILREDTF LGLESLEYLQ ADYNYISAIE AGAFSKLNKL KVLILNDNLL LSLPSNVFRF
190 200 210 220 230 240
VLLTHLDLRG NRLKVMPFAG VLEHIGGIME IQLEENPWNC TCDLLPLKAW LDTITVFVGE
250 260 270 280 290 300
IVCETPFRLH GKDVTQLTRQ DLCPRKSASD SSQRGSHADT HVQRLSPTMN PALNPTRAPK
310 320 330 340 350 360
ASRPPKMRNR PTPRVTVSKD RQSFGPIMVY QTKSPVPLTC PSSCVCTSQS SDNGLNVNCQ
370 380 390 400 410 420
ERKFTNISDL QPKPTSPKKL YLTGNYLQTV YKNDLLEYSS LDLLHLGNNR IAVIQEGAFT
430 440 450 460 470 480
NLTSLRRLYL NGNYLEVLYP SMFDGLQSLQ YLYLEYNVIK EIKPLTFDAL INLQLLFLNN
490 500 510 520 530 540
NLLRSLPDNI FGGTALTRLN LRNNHFSHLP VKGVLDQLPA FIQIDLQENP WDCTCDIMGL
550 560 570 580 590 600
KDWTEHANSP VIINEVTCES PAKHAGEILK FLGREAICPD SPNLSDGTVL SMNHNTDTPR
610 620 630 640 650 660
SLSVSPSSYP ELHTEVPLSV LILGLLVVFI LSVCFGAGLF VFVLKRRKGV PSVPRNTNNL
670 680 690 700 710 720
DVSSFQLQYG SYNTETHDKT DGHVYNYIPP PVGQMCQNPI YMQKEGDPVA YYRNLQEFSY
730 740 750 760 770 780
SNLEEKKEEP ATPAYTISAT ELLEKQATPR EPELLYQNIA ERVKELPSAG LVHYNFCTLP
790 800 810 820 830 840
KRQFAPSYES RRQNQDRINK TVLYGTPRKC FVGQSKPNHP LLQAKPQSEP DYLEVLEKQT
AISQL
CATM prediction
The sequence of SLIK2_HUMAN returned 1 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 620 630 640 | + | + | + |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | SVLILGLLVVFILSVCFGAGLFVFVLK | 7.3 | -55.1° | 2.4 | 48.3 | -8.2 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 633, VAL, HA | A, 632, SER, O | 3.33Å |
| B, 636, GLY, HA1 | A, 633, VAL, O | 3.13Å |
| A, 633, VAL, HA | B, 632, SER, O | 3.33Å |
| A, 636, GLY, HA1 | B, 633, VAL, O | 3.13Å |