UniProt data
UniProt name: TMG4_HUMAN (Q9BZD6)
Gene name: PRRG4; Synonyms=PRGP4, TMG4
Organism: Homo sapiens (Human).
Function:
Subcellular location: Membrane; Single-pass type I membrane protein.
Transmembrane domains:
- 114-134, 21 AA, Helical. {ECO:0000255}.
Sequence: 226 AA
10 20 30 40 50 60
MFTLLVLLSQ LPTVTLGFPH CARGPKASKH AGEEVFTSKE EANFFIHRRL LYNRFDLELF
70 80 90 100 110 120
TPGNLERECN EELCNYEEAR EIFVDEDKTI AFWQEYSAKG PTTKSDGNRE KIDVMGLLTG
130 140 150 160 170 180
LIAAGVFLVI FGLLGYYLCI TKCNRLQHPC SSAVYERGRH TPSIIFRRPE EAALSPLPPS
190 200 210 220
VEDAGLPSYE QAVALTRKHS VSPPPPYPGH TKGFRVFKKS MSLPSH
CATM prediction
The sequence of TMG4_HUMAN returned 4 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 120 130 + | + | + |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | KIDVMGLLTGLIAAGVFLVIFGLLGYY | 6.7 | -47.0° | 3.8 | 53.5 | -28.5 |
| Model 2 | KIDVMGLLTGLIAAGVFLVIFGLLGYY | 7.4 | -22.0° | 3.1 | 40.0 | -24.1 |
| Model 3 | KIDVMGLLTGLIAAGVFLVIFGLLGYY | 7.0 | +54.2° | 3.3 | 80.2 | -11.9 |
| Model 4 | KIDVMGLLTGLIAAGVFLVIFGLLGYY | 6.8 | -55.0° | 0.9 | 50.0 | -3.2 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 117, LEU, HA | A, 116, GLY, O | 2.66Å |
| B, 120, GLY, HA1 | A, 117, LEU, O | 2.94Å |
| A, 117, LEU, HA | B, 116, GLY, O | 2.66Å |
| A, 120, GLY, HA1 | B, 117, LEU, O | 2.94Å |
