UniProt data
UniProt name: PC11Y_HUMAN (Q9BZA8)
Gene name: PCDH11Y; Synonyms=PCDH11, PCDH22, PCDHY
Organism: Homo sapiens (Human).
Function: Potential calcium-dependent cell-adhesion protein.
Subcellular location: Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Transmembrane domains:
- 845-865, 21 AA, Helical. {ECO:0000255}.
Sequence: 1340 AA
10 20 30 40 50 60
MFRVGFLIIS SSSSLSPLLL VSVVRVNTTN CHKCLLSGTY IFAVLLVCVV FHSGAQEKNY
70 80 90 100 110 120
TIREEIPENV LIGNLLKDLN LSLIPNKSLT TTMQFKLVYK TGDVPLIRIE EDTGEIFTTG
130 140 150 160 170 180
ARIDREKLCA GIPRDEHCFY EVEVAILPDE IFRLVKIRFL IEDINDNAPL FPATVINISI
190 200 210 220 230 240
PENSAINSKY TLPAAVDPDV GINGVQNYEL IKSQNIFGLD VIETPEGDKM PQLIVQKELD
250 260 270 280 290 300
REEKDTYVMK VKVEDGGFPQ RSSTAILQVS VTDTNDNHPV FKETEIEVSI PENAPVGTSV
310 320 330 340 350 360
TQLHATDADI GENAKIHFSF SNLVSNIARR LFHLNATTGL ITIKEPLDRE ETPNHKLLVL
370 380 390 400 410 420
ASDGGLMPAR AMVLVNVTDV NDNVPSIDIR YIVNPVNDTV VLSENIPLNT KIALITVTDK
430 440 450 460 470 480
DADHNGRVTC FTDHEIPFRL RPVFSNQFLL ENAAYLDYES TKEYAIKLLA ADAGKPPLNQ
490 500 510 520 530 540
SAMLFIKVKD ENDNAPVFTQ SFVTVSIPEN NSPGIQLMKV SATDADSGPN AEINYLLGPD
550 560 570 580 590 600
APPEFSLDRR TGMLTVVKKL DREKEDKYLF TILAKDNGVP PLTSNVTVFV SIIDQNDNSP
610 620 630 640 650 660
VFTHNEYKFY VPENLPRHGT VGLITVTDPD YGDNSAVTLS ILDENDDFTI DSQTGVIRPN
670 680 690 700 710 720
ISFDREKQES YTFYVKAEDG GRVSRSSSAK VTINVVDVND NKPVFIVPPY NYSYELVLPS
730 740 750 760 770 780
TNPGTVVFQV IAVDNDTGMN AEVRYSIVGG NTRDLFAIDQ ETGNITLMEK CDVTDLGLHR
790 800 810 820 830 840
VLVKANDLGQ PDSLFSVVIV NLFVNESVTN ATLINELVRK SIEAPVTPNT EIADVSSPTS
850 860 870 880 890 900
DYVKILVAAV AGTITVVVVI FITAVVRCRQ APHLKAAQKN MQNSEWATPN PENRQMIMMK
910 920 930 940 950 960
KKKKKKKHSP KNLLLNVVTI EETKADDVDS DGNRVTLDLP IDLEEQTMGK YNWVTTPTTF
970 980 990 1000 1010 1020
KPDSPDLARH YKSASPQPAF QIQPETPLNL KHHIIQELPL DNTFVACDSI SNCSSSSSDP
1030 1040 1050 1060 1070 1080
YSVSDCGYPV TTFEVPVSVH TRPSQRRVTF HLPEGSQESS SDGGLGDHDA GSLTSTSHGL
1090 1100 1110 1120 1130 1140
PLGYPQEEYF DRATPSNRTE GDGNSDPEST FIPGLKKEIT VQPTVEEASD NCTQECLIYG
1150 1160 1170 1180 1190 1200
HSDACWMPAS LDHSSSSQAQ ASALCHSPPL SQASTQHHSP PVTQTIVLCH SPPVTQTIAL
1210 1220 1230 1240 1250 1260
CHSPPPIQVS ALHHSPPLVQ GTALHHSPPS AQASALCYSP PLAQAAAISH SSSLPQVIAL
1270 1280 1290 1300 1310 1320
HRSQAQSSVS LQQGWVQGAN GLCSVDQGVQ GSATSQFYTM SERLHPSDDS IKVIPLTTFA
1330
PRQQARPSRG DSPIMETHPL
CATM prediction
The sequence of PC11Y_HUMAN returned 1 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 850 860 + | + | + |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | YVKILVAAVAGTITVVVVIFITAVVRC | 7.2 | -51.0° | 4.3 | 40.0 | -21.9 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 849, ALA, HA | A, 848, ALA, O | 2.97Å |
| B, 852, GLY, HA1 | A, 849, ALA, O | 3.20Å |
| A, 849, ALA, HA | B, 848, ALA, O | 2.97Å |
| A, 852, GLY, HA1 | B, 849, ALA, O | 3.20Å |