UniProt data
UniProt name: B2L13_HUMAN (Q9BXK5)
Gene name: BCL2L13; Synonyms=MIL1; ORFNames=CD003
Organism: Homo sapiens (Human).
Function: May promote the activation of caspase-3 and apoptosis.
Subcellular location: Isoform 1: Nucleus {ECO:0000305}.
Transmembrane domains:
- 460-480, 21 AA, Helical. {ECO:0000255}.
Sequence: 485 AA
10 20 30 40 50 60
MASSSTVPLG FHYETKYVVL SYLGLLSQEK LQEQHLSSPQ GVQLDIASQS LDQEILLKVK
70 80 90 100 110 120
TEIEEELKSL DKEISEAFTS TGFDRHTSPV FSPANPESSM EDCLAHLGEK VSQELKEPLH
130 140 150 160 170 180
KALQMLLSQP VTYQAFRECT LETTVHASGW NKILVPLVLL RQMLLELTRR GQEPLSALLQ
190 200 210 220 230 240
FGVTYLEDYS AEYIIQQGGW GTVFSLESEE EEYPGITAED SNDIYILPSD NSGQVSPPES
250 260 270 280 290 300
PTVTTSWQSE SLPVSLSASQ SWHTESLPVS LGPESWQQIA MDPEEVKSLD SNGAGEKSEN
310 320 330 340 350 360
NSSNSDIVHV EKEEVPEGME EAAVASVVLP ARELQEALPE APAPLLPHIT ATSLLGTREP
370 380 390 400 410 420
DTEVITVEKS SPATSLFVEL DEEEVKAATT EPTEVEEVVP ALEPTETLLS EKEINAREES
430 440 450 460 470 480
LVEELSPASE KKPVPPSEGK SRLSPAGEMK PMPLSEGKSI LLFGGAAAVA ILAVAIGVAL
ALRKK
CATM prediction
The sequence of B2L13_HUMAN returned 2 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 460 470 480 | + | + | |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | GKSILLFGGAAAVAILAVAIGVALALR | 6.9 | -46.0° | 2.7 | 46.9 | -25.2 |
| Model 2 | GKSILLFGGAAAVAILAVAIGVALALR | 6.9 | -54.9° | 1.6 | 44.7 | -14.7 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 474, VAL, HA | A, 473, ALA, O | 3.00Å |
| B, 477, GLY, HA1 | A, 474, VAL, O | 2.95Å |
| A, 474, VAL, HA | B, 473, ALA, O | 3.00Å |
| A, 477, GLY, HA1 | B, 474, VAL, O | 2.95Å |
