Small integral membrane protein 2

UniProt data

UniProt name: SMIM2_HUMAN (Q9BVW6)

Gene name: SMIM2; Synonyms=C13orf44

Organism: Homo sapiens (Human).

Function:

Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.

Transmembrane domains:

  1. 21-43, 23 AA, Helical. {ECO:0000255}.

Sequence: 85 AA

10 20 30 40 50 60 MEAGERIDAS QLPHRVLETR GHAISILFGF WTSFICDTYI VLAWISKIKG SPDVSASSDE 70 80 PYARIQQSRR QCHAEEDQSQ VPEAG

CATM prediction

The sequence of SMIM2_HUMAN returned 1 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
    20        30        40     
  |    +    |    +    |    + 
(Å) (°) (Å) (°)  
ETRGHAISILFGFWTSFICDTYIVLAWIS 7.1 -43.7° 1.8 45.0 -23.8

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


Click on the image to enlarge

Download model 1 structure: PDB, PyMOL session

List of hydrogen bonds:

Donor Acceptor Distance
B, 22, HSE, HA A, 22, HSE, ND1 3.35Å
B, 25, SER, HG1 A, 22, HSE, ND1 1.81Å
B, 26, ILE, HA A, 25, SER, O 3.30Å
B, 29, GLY, HA1 A, 26, ILE, O 3.09Å
B, 30, PHE, HA A, 29, GLY, O 3.38Å
B, 33, SER, HG1 A, 30, PHE, O 2.49Å
A, 22, HSE, HA B, 22, HSE, ND1 3.40Å
A, 26, ILE, HA B, 25, SER, O 3.30Å
A, 29, GLY, HA1 B, 26, ILE, O 3.09Å
A, 30, PHE, HA B, 29, GLY, O 3.38Å
A, 33, SER, HG1 B, 30, PHE, O 2.49Å