UniProt data
UniProt name: MXRA8_HUMAN (Q9BRK3)
Gene name: MXRA8
Organism: Homo sapiens (Human).
Function: May play a role in the maturation and maintenance of blood-brain barrier. {ECO:0000250}.
Subcellular location: Membrane; Single-pass type I membrane protein.
Transmembrane domains:
- 342-362, 21 AA, Helical. {ECO:0000255}.
Sequence: 442 AA
10 20 30 40 50 60
MALPSRILLW KLVLLQSSAV LLHSGSSVPA AAGSSVVSES AVSWEAGARA VLRCQSPRMV
70 80 90 100 110 120
WTQDRLHDRQ RVLHWDLRGP GGGPARRLLD LYSAGEQRVY EARDRGRLEL SASAFDDGNF
130 140 150 160 170 180
SLLIRAVEET DAGLYTCNLH HHYCHLYESL AVRLEVTDGP PATPAYWDGE KEVLAVARGA
190 200 210 220 230 240
PALLTCVNRG HVWTDRHVEE AQQVVHWDRQ PPGVPHDRAD RLLDLYASGE RRAYGPLFLR
250 260 270 280 290 300
DRVAVGADAF ERGDFSLRIE PLEVADEGTY SCHLHHHYCG LHERRVFHLT VAEPHAEPPP
310 320 330 340 350 360
RGSPGNGSSH SGAPGPDPTL ARGHNVINVI VPESRAHFFQ QLGYVLATLL LFILLLVTVL
370 380 390 400 410 420
LAARRRRGGY EYSDQKSGKS KGKDVNLAEF AVAAGDQMLY RSEDIQLDYK NNILKERAEL
430 440
AHSPLPAKYI DLDKGFRKEN CK
CATM prediction
The sequence of MXRA8_HUMAN returned 1 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 340 350 360 | + | + | + |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | FQQLGYVLATLLLFILLLVTVLLAARR | 7.4 | -43.0° | 3.5 | 50.0 | -2.7 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session