Protein FAM173A

UniProt data

UniProt name: F173A_HUMAN (Q9BQD7)

Gene name: FAM173A; Synonyms=C16orf24; ORFNames=RJD7

Organism: Homo sapiens (Human).

Function:

Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.

Transmembrane domains:

  1. 20-42, 23 AA, Helical. {ECO:0000255}.

Sequence: 235 AA

10 20 30 40 50 60 MEQDDPVEAL TELRERRLGA LELLQAAAGS GLAAYAVWAL LLQPGFRRVP LRLQVPYVGA 70 80 90 100 110 120 SARQVEHVLS LLRGRPGKTV DLGSGDGRIV LAAHRCGLRP AVGYELNPWL VALARLHAWR 130 140 150 160 170 180 AGCAGSVCYR RKDLWKVSLR DCRNVSVFLA PSVLPLLEDK LRTELPAGAR VVSGRFPLPT 190 200 210 220 230 WQPVTAVGEG LDRVWAYDVP EGGQAGEAAS SRIPIQAAPG PSSAPIPGGL ISQAS

CATM prediction

The sequence of F173A_HUMAN returned 2 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
     20        30        40    
   |    +    |    +    |    +		 (Å) (°) (Å) (°)  
Model 1 RLGALELLQAAAGSGLAAYAVWALLLQAG 7.1 -44.3° 1.8 44.9 -17.6
Model 2 RLGALELLQAAAGSGLAAYAVWALLLQAG 7.1 -48.0° 5.2 38.5 -11.4
Prolines* RLGALELLQAAAGSGLAAYAVWALLLQPG          

* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


Click on the image to enlarge

Download model 1 structure: PDB, PyMOL session

List of hydrogen bonds:

Donor Acceptor Distance
B, 26, ALA, HA A, 25, GLN, O 3.29Å
B, 29, GLY, HA1 A, 26, ALA, O 3.07Å
B, 30, SER, HA A, 29, GLY, O 3.39Å
A, 22, GLU, HA B, 22, GLU, OE1 3.32Å
A, 25, GLN, HE21 B, 22, GLU, OE1 2.23Å
A, 22, GLU, HA B, 22, GLU, OE2 3.30Å
A, 26, ALA, HA B, 25, GLN, O 3.29Å
A, 29, GLY, HA1 B, 26, ALA, O 3.07Å
A, 30, SER, HA B, 29, GLY, O 3.39Å