cTAGE family member 2

UniProt data

UniProt name: CTGE2_HUMAN (Q96RT6)

Gene name: CTAGE1; Synonyms=CTAGE2

Organism: Homo sapiens (Human).

Function:

Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.

Transmembrane domains:

  1. 13-30, 18 AA, Helical. {ECO:0000255}.

Sequence: 745 AA

10 20 30 40 50 60 MRPDSHPYGF PWELVIRAAV AGFFAVLFLW RSFRSVTSRL YVRREKKFAV ALSGLIEEKC 70 80 90 100 110 120 KLLEKFSLVQ KEYEGYEVES SLKNASFEKE ATEAQSLEAT CEKLNRFNSE LVHEILCLEK 130 140 150 160 170 180 ELKEEKSKHS EQNELMADIS KRIQSLEDES KSLKSQVAEA KMTFKRFQAN EERLEIEIQD 190 200 210 220 230 240 AWKENSELQE SQKQLLQEAE VWKEQVSELI KQKRTFEDSK VHAEQVLNDK ENHIKTLTER 250 260 270 280 290 300 LLKMKDGVAM LEEDVTDDDN LELEMNSESE DGAYLDNPPK GALKKLIHAA KLNASLKTLE 310 320 330 340 350 360 GERNQIYIQL SEVDKTKEEL TEHIKNLQTE QASLQSENTH FESENQKLQQ KLKVMTELYQ 370 380 390 400 410 420 ENEMKLYRKL IVEEKCRLEK EEKLSKVDEM ISHATEELET YRKRAKDLKE FEKTIHFYQK 430 440 450 460 470 480 KIILHEKKAH DNWSAAWTAE RNLNDLRKEN AHNRQKLTEI EFKIKLLEKD PYGLDVPNTA 490 500 510 520 530 540 FGRQHSPYGP SPLGWPSSET RASLYPPTLL EGPLRLSPLL PRGGGRGSRG PGNPPDHQIT 550 560 570 580 590 600 KERGESSCDR LTDPHRAPSD AGPLAPPWEQ DYRMMFPPPG QSYPDSALPP QRQDRFYSNC 610 620 630 640 650 660 ARLSGPAELR SFNMPSLDKM DGSMPSEMES SRNDTKDNLG NLKVPDSSLP AENEATGPGF 670 680 690 700 710 720 VPPPLAPIRG LLFPVDTRGP FIRRGPPFPP PPPGTVFGAS PDYFSPRDVP GPPRAPFAMR 730 740 NVYLPRGFLP YRPPRPAFFP PAPTF

CATM prediction

The sequence of CTGE2_HUMAN returned 1 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
  10        20        30  
|    +    |    +    |   		 (Å) (°) (Å) (°)  
Model 1 FAWELVIRAAVAGFFAVLFLWRSF 7.1 -54.0° 4.8 41.1 -16.3
Prolines* FPWELVIRAAVAGFFAVLFLWRSF          

* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


Click on the image to enlarge

Download model 1 structure: PDB, PyMOL session

List of hydrogen bonds:

Donor Acceptor Distance
B, 19, ALA, HA A, 18, ALA, O 3.06Å
B, 22, GLY, HA1 A, 19, ALA, O 3.46Å
A, 19, ALA, HA B, 18, ALA, O 3.06Å
A, 22, GLY, HA1 B, 19, ALA, O 3.46Å