UniProt data
UniProt name: FCRL3_HUMAN (Q96P31)
Gene name: FCRL3; Synonyms=FCRH3, IFGP3, IRTA3, SPAP2
Organism: Homo sapiens (Human).
Function:
Subcellular location: Cell membrane {ECO:0000269|PubMed:16849395}; Single-pass type I membrane protein {ECO:0000269|PubMed:16849395}.
Transmembrane domains:
- 574-594, 21 AA, Helical. {ECO:0000255}.
Sequence: 734 AA
10 20 30 40 50 60
MLLWLLLLIL TPGREQSGVA PKAVLLLNPP WSTAFKGEKV ALICSSISHS LAQGDTYWYH
70 80 90 100 110 120
DEKLLKIKHD KIQITEPGNY QCKTRGSSLS DAVHVEFSPD WLILQALHPV FEGDNVILRC
130 140 150 160 170 180
QGKDNKNTHQ KVYYKDGKQL PNSYNLEKIT VNSVSRDNSK YHCTAYRKFY ILDIEVTSKP
190 200 210 220 230 240
LNIQVQELFL HPVLRASSST PIEGSPMTLT CETQLSPQRP DVQLQFSLFR DSQTLGLGWS
250 260 270 280 290 300
RSPRLQIPAM WTEDSGSYWC EVETVTHSIK KRSLRSQIRV QRVPVSNVNL EIRPTGGQLI
310 320 330 340 350 360
EGENMVLICS VAQGSGTVTF SWHKEGRVRS LGRKTQRSLL AELHVLTVKE SDAGRYYCAA
370 380 390 400 410 420
DNVHSPILST WIRVTVRIPV SHPVLTFRAP RAHTVVGDLL ELHCESLRGS PPILYRFYHE
430 440 450 460 470 480
DVTLGNSSAP SGGGASFNLS LTAEHSGNYS CDADNGLGAQ HSHGVSLRVT VPVSRPVLTL
490 500 510 520 530 540
RAPGAQAVVG DLLELHCESL RGSFPILYWF YHEDDTLGNI SAHSGGGASF NLSLTTEHSG
550 560 570 580 590 600
NYSCEADNGL GAQHSKVVTL NVTGTSRNRT GLTAAGITGL VLSILVLAAA AALLHYARAR
610 620 630 640 650 660
RKPGGLSATG TSSHSPSECQ EPSSSRPSRI DPQEPTHSKP LAPMELEPMY SNVNPGDSNP
670 680 690 700 710 720
IYSQIWSIQH TKENSANCPM MHQEHEELTV LYSELKKTHP DDSAGEASSR GRAHEEDDEE
730
NYENVPRVLL ASDH
CATM prediction
The sequence of FCRL3_HUMAN returned 1 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 580 590 + | + | + |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | GLTAAGITGLVLSILVLAAAAALLHYA | 7.0 | -49.0° | 3.9 | 38.1 | -15.8 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 576, GLY, HA2 | A, 575, ALA, O | 2.98Å |
| B, 579, GLY, HA1 | A, 576, GLY, O | 3.11Å |
| A, 576, GLY, HA2 | B, 575, ALA, O | 2.98Å |
| A, 579, GLY, HA1 | B, 576, GLY, O | 3.11Å |
| A, 580, LEU, HA | B, 583, SER, OG | 3.35Å |
| A, 583, SER, HG1 | B, 583, SER, OG | 2.05Å |