Contactin-associated protein-like 3B

UniProt data

UniProt name: CNT3B_HUMAN (Q96NU0)

Gene name: CNTNAP3B; Synonyms=CASPR3B

Organism: Homo sapiens (Human).

Function:

Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.

Transmembrane domains:

  1. 1246-1266, 21 AA, Helical. {ECO:0000255}.

Sequence: 1288 AA

10 20 30 40 50 60 MASVAWAVLK VLLLLPTQTW SPVGAGNPPD CDSPLASALP RSSFSSSSEL SSSHGPGFSR 70 80 90 100 110 120 LNRRDGAGGW TPLVSNKYQW LQIDLGERME VTAVATQGGY GSSDWVTSYL LMFSDGGRNW 130 140 150 160 170 180 KQYRREESIW GFPGNTNADS VVHYRLQPPF EARFLRFLPL AWNPRGRIGM RIEVYGCAYK 190 200 210 220 230 240 SEVVYFDGQS ALLYTLDKKP LKPIRDVISL KFKAMQSNGI LLHREGQHGN HITLELIKGK 250 260 270 280 290 300 LVFFLNSGNA KLPSTIAPVT LTLGSLLDDQ HWHSVLIELL DTQVNFTVDK HTHHFQAKGD 310 320 330 340 350 360 SSNLDLNFEI SFGGILSPGR SRAFTRKSFH GCLENLYYNG VDVTELAKKH KPQILMMGNV 370 380 390 400 410 420 SFSCPQPQTV PVTFLSSRSY LALPGNSGED KVSVTFQFRT WNRAGHLLFG ELQRGSGSFV 430 440 450 460 470 480 LFLKDGKLKL SLFQAGQSPR NVTAGAGLND GQWHSVSFSA KWSHMNVVVD DDTAVQPLVA 490 500 510 520 530 540 VLIDSGDTYY FGGCLGNSSG SGCKSPLGGF QGCLRLITIG DKAVDPILVQ QGALGSFRDL 550 560 570 580 590 600 QIDSCGITDR CLPSYCEHGG ECSQSWDTFS CDCLGTGYTG ETCHSSLYEQ SCEAHKHRGN 610 620 630 640 650 660 PSGLYYIDAD GSGPLGPFLV YCNMTADSAW TVVRHGGPDA VTLRGAPSGH PLSAVSFAYA 670 680 690 700 710 720 AGAGQLRAAV NLAERCEQRL ALRCGTARRP DSRDGTPLSW WVGRTNETHT SWGGSLPDAQ 730 740 750 760 770 780 KCTCGLEGNC IDSQYYCNCD AGQNEWTSDT IVLSQKEHLP VTQIVMTDTG QPHSEADYTL 790 800 810 820 830 840 GPLLCRGDKS FWNSASFNTE TSYLHFPAFH GELTADVCFF FKTTVSSGVF MENLGITDFI 850 860 870 880 890 900 RIELRAPTEV TFSFDVGNGP CEVTVQSPTP FNDNQWHHVR AERNVKGASL QVDQLPQKMQ 910 920 930 940 950 960 PAPADGHVRL QLNSQLFIGG TATRQRGFLG CIRSLQLNGV ALDLEERATV TPGVEPGCAG 970 980 990 1000 1010 1020 HCSTYGHLCR NGGRCREKRR GVTCDCAFSA YDGPFCSNEI SAYFATGSSM TYHFQEHYTL 1030 1040 1050 1060 1070 1080 SENSSSLVSS LYRDVTLTRE MITLSFRTTR SPSLLLYVSS FYEEYLSVIL ANNGSLQIRY 1090 1100 1110 1120 1130 1140 KLDRHQNPDA FTFDFKNMAD GQLHQVKINR EEAVVMVEVN QSAKKQVILS SGTEFNAVKS 1150 1160 1170 1180 1190 1200 LILGKVLEAA GADPDTRRAA TSGFTGCLSA VRFGRAAPLK AALRPSGPSR VTVRGHVAPM 1210 1220 1230 1240 1250 1260 ARCAAGAASG SPARELAPRL AGGAGRSGPV DEGEPLVNAD RRDSAVMGGV IAVVIFILLC 1270 1280 ITAIAIRIYQ QRKLRKENES KVSKKEEC

CATM prediction

The sequence of CNT3B_HUMAN returned 2 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
         1250      1260      
  +    |    +    |    +    		 (Å) (°) (Å) (°)  
Model 1 DSAVMGGVIAVVIFILLCITAIAIRIY 6.9 -40.0° 4.0 38.0 -19.2
Model 2 DSAVMGGVIAVVIFILLCITAIAIRIY 6.6 -54.0° 3.6 35.0 -5.5

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


Click on the image to enlarge

Download model 1 structure: PDB, PyMOL session