Putative uncharacterized protein C8orf49

UniProt data

UniProt name: CH049_HUMAN (Q96NF6)

Gene name: C8orf49

Organism: Homo sapiens (Human).

Function:

Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.

Transmembrane domains:

  1. 110-130, 21 AA, Helical. {ECO:0000255}.

Sequence: 230 AA

10 20 30 40 50 60 MEKPRLYQKY KISRVWWRLP VIPATREAED NRLNPEGRGC GEPRSRHCTP AWTTTAKLHL 70 80 90 100 110 120 KTIISLQPLN MYQMEPGVGS IRTSPALQSP PALTRGPSAW DTAIRKALSF GVGLGVLVLV 130 140 150 160 170 180 CLFYHFVTLA PILQFASLPC LLEAGAQMSR HPVTTQVCIM PARLSLGSGI SRNLLRLSVC 190 200 210 220 HFTLLLPFRS LRPCPLSSRD MVLSYELWLL CDFYIAPPDS SGSGICKKAI

CATM prediction

The sequence of CH049_HUMAN returned 2 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
     110       120       130 
   |    +    |    +    |   
(Å) (°) (Å) (°)  
ALSFGVGLGVLVLVCLFYHFVTLAAIL 7.0 -32.0° 5.8 44.0 -12.5
ALSFGVGLGVLVLVCLFYHFVTLAAIL 7.4 -50.0° 2.9 47.0 -7.9
ALSFGVGLGVLVLVCLFYHFVTLAPIL          

* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


Click on the image to enlarge

Download model 1 structure: PDB, PyMOL session