UniProt data
UniProt name: TIM14_HUMAN (Q96DA6)
Gene name: DNAJC19; Synonyms=TIM14, TIMM14
Organism: Homo sapiens (Human).
Function: Probable component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. May act as a co-chaperone that stimulate the ATP-dependent activity (By similarity). {ECO:0000250}.
Subcellular location: Mitochondrion inner membrane {ECO:0000305|PubMed:12592411}; Single-pass membrane protein {ECO:0000305|PubMed:12592411}.
Transmembrane domains:
- 4-24, 21 AA, Helical. {ECO:0000255}.
Sequence: 116 AA
CATM prediction
The sequence of TIM14_HUMAN returned 1 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 10 20 + | + | + |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | MASTVVAVGLTIAAAGFAGRYVLQAMK | 6.7 | -55.2° | 4.2 | 37.4 | -4.8 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 16, GLY, HA2 | A, 15, ALA, O | 2.81Å |
| B, 19, GLY, HA1 | A, 16, GLY, O | 2.99Å |
| B, 20, ARG, HE | A, 19, GLY, O | 2.56Å |
| A, 16, GLY, HA2 | B, 15, ALA, O | 2.81Å |
| A, 19, GLY, HA1 | B, 16, GLY, O | 2.99Å |
| A, 20, ARG, HE | B, 19, GLY, O | 2.56Å |