Golgi apparatus protein 1

UniProt data

UniProt name: GSLG1_HUMAN (Q92896)

Gene name: GLG1; Synonyms=CFR1, ESL1, MG160

Organism: Homo sapiens (Human).

Function: Binds fibroblast growth factor and E-selectin (cell- adhesion lectin on endothelial cells mediating the binding of neutrophils).

Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:2355176}; Single-pass type I membrane protein {ECO:0000269|PubMed:2355176}.

Transmembrane domains:

  1. 1146-1166, 21 AA, Helical. {ECO:0000255}.

Sequence: 1179 AA

10 20 30 40 50 60 MAACGRVRRM FRLSAALHLL LLFAAGAEKL PGQGVHSQGQ GPGANFVSFV GQAGGGGPAG 70 80 90 100 110 120 QQLPQLPQSS QLQQQQQQQQ QQQQPQPPQP PFPAGGPPAR RGGAGAGGGW KLAEEESCRE 130 140 150 160 170 180 DVTRVCPKHT WSNNLAVLEC LQDVREPENE ISSDCNHLLW NYKLNLTTDP KFESVAREVC 190 200 210 220 230 240 KSTITEIKEC ADEPVGKGYM VSCLVDHRGN ITEYQCHQYI TKMTAIIFSD YRLICGFMDD 250 260 270 280 290 300 CKNDINILKC GSIRLGEKDA HSQGEVVSCL EKGLVKEAEE REPKIQVSEL CKKAILRVAE 310 320 330 340 350 360 LSSDDFHLDR HLYFACRDDR ERFCENTQAG EGRVYKCLFN HKFEESMSEK CREALTTRQK 370 380 390 400 410 420 LIAQDYKVSY SLAKSCKSDL KKYRCNVENL PRSREARLSY LLMCLESAVH RGRQVSSECQ 430 440 450 460 470 480 GEMLDYRRML MEDFSLSPEI ILSCRGEIEH HCSGLHRKGR TLHCLMKVVR GEKGNLGMNC 490 500 510 520 530 540 QQALQTLIQE TDPGADYRID RALNEACESV IQTACKHIRS GDPMILSCLM EHLYTEKMVE 550 560 570 580 590 600 DCEHRLLELQ YFISRDWKLD PVLYRKCQGD ASRLCHTHGW NETSEFMPQG AVFSCLYRHA 610 620 630 640 650 660 YRTEEQGRRL SRECRAEVQR ILHQRAMDVK LDPALQDKCL IDLGKWCSEK TETGQELECL 670 680 690 700 710 720 QDHLDDLVVE CRDIVGNLTE LESEDIQIEA LLMRACEPII QNFCHDVADN QIDSGDLMEC 730 740 750 760 770 780 LIQNKHQKDM NEKCAIGVTH FQLVQMKDFR FSYKFKMACK EDVLKLCPNI KKKVDVVICL 790 800 810 820 830 840 STTVRNDTLQ EAKEHRVSLK CRRQLRVEEL EMTEDIRLEP DLYEACKSDI KNFCSAVQYG 850 860 870 880 890 900 NAQIIECLKE NKKQLSTRCH QKVFKLQETE MMDPELDYTL MRVCKQMIKR FCPEADSKTM 910 920 930 940 950 960 LQCLKQNKNS ELMDPKCKQM ITKRQITQNT DYRLNPMLRK ACKADIPKFC HGILTKAKDD 970 980 990 1000 1010 1020 SELEGQVISC LKLRYADQRL SSDCEDQIRI IIQESALDYR LDPQLQLHCS DEISSLCAEE 1030 1040 1050 1060 1070 1080 AAAQEQTGQV EECLKVNLLK IKTELCKKEV LNMLKESKAD IFVDPVLHTA CALDIKHHCA 1090 1100 1110 1120 1130 1140 AITPGRGRQM SCLMEALEDK RVRLQPECKK RLNDRIEMWS YAAKVAPADG FSDLAMQVMT 1150 1160 1170 SPSKNYILSV ISGSICILFL IGLMCGRITK RVTRELKDR

CATM prediction

The sequence of GSLG1_HUMAN returned 1 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
         1150      1160      
  +    |    +    |    +    		 (Å) (°) (Å) (°)  
Model 1 SKNYILSVISGSICILFLIGLMCGRIT 7.3 -48.0° 0.7 54.4 -24.4

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


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Download model 1 structure: PDB, PyMOL session

List of hydrogen bonds:

Donor Acceptor Distance
B, 1162, GLY, HA1 A, 1159, PHE, O 3.45Å
B, 1163, LEU, HA A, 1162, GLY, O 3.33Å
A, 1162, GLY, HA1 B, 1159, PHE, O 3.45Å
A, 1163, LEU, HA B, 1162, GLY, O 3.33Å