Small integral membrane protein 4

UniProt data

UniProt name: SMIM4_HUMAN (Q8WVI0)

Gene name: SMIM4; Synonyms=C3orf78

Organism: Homo sapiens (Human).

Function:

Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.

Transmembrane domains:

  1. 20-41, 22 AA, Helical. {ECO:0000255}.

Sequence: 70 AA

10 20 30 40 50 60 MFTRAQVRRI LQRVPGKQRF GIYRFLPFFF VLGGTMEWIM IKVRVGQETF YDVYRRKASE RQYQRRLEDE

CATM prediction

The sequence of SMIM4_HUMAN returned 2 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
     20        30        40   
   |    +    |    +    |    
(Å) (°) (Å) (°)  
KQRFGIYRFLAFFFVLGGTMEWIMIKVR 6.6 -54.9° 0.9 50.1 -5.1
KQRFGIYRFLAFFFVLGGTMEWIMIKVR 7.3 -55.0° 4.2 38.0 -5.0
KQRFGIYRFLPFFFVLGGTMEWIMIKVR          

* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


Click on the image to enlarge

Download model 1 structure: PDB, PyMOL session

List of hydrogen bonds:

Donor Acceptor Distance
B, 30, PHE, HA A, 29, PHE, O 3.34Å
B, 33, GLY, HA1 A, 30, PHE, O 2.65Å
B, 34, GLY, HA2 A, 33, GLY, O 2.95Å
B, 34, GLY, HA1 A, 37, GLU, OE1 3.11Å
A, 30, PHE, HA B, 29, PHE, O 3.34Å
A, 33, GLY, HA1 B, 30, PHE, O 2.65Å
A, 34, GLY, HA2 B, 33, GLY, O 2.95Å
A, 34, GLY, HA1 B, 37, GLU, OE1 3.11Å