Cytochrome c oxidase subunit 7B2, mitochondrial

UniProt data

UniProt name: CX7B2_HUMAN (Q8TF08)

Gene name: COX7B2

Organism: Homo sapiens (Human).

Function: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.

Subcellular location: Mitochondrion inner membrane {ECO:0000250}.

Transmembrane domains:

  1. 34-60, 27 AA, Helical. {ECO:0000250}.

Sequence: 81 AA

10 20 30 40 50 60 MMFPLARNAL SSLKIQSILQ SMARHSHVKH SPDFHDKYGN AVLASGTAFC VATWVFTATQ 70 80 IGIEWNLSPV GRVTPKEWKH Q

CATM prediction

The sequence of CX7B2_HUMAN returned 2 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
           40        50        60  
    +    |    +    |    +    |   		 (Å) (°) (Å) (°)  
Model 1 SADFHDKYGNAVLASGTAFCVATWVFTATQIGI 7.2 -36.9° 2.3 36.1 -24.9
Model 2 SADFHDKYGNAVLASGTAFCVATWVFTATQIGI 7.4 -42.8° 2.4 44.2 -7.8
Prolines* SPDFHDKYGNAVLASGTAFCVATWVFTATQIGI          

* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


Click on the image to enlarge

Download model 1 structure: PDB, PyMOL session

List of hydrogen bonds:

Donor Acceptor Distance
B, 37, LYS, HZ3 A, 36, ASP, OD2 2.11Å
B, 41, ALA, HA A, 40, ASN, O 3.47Å
B, 45, SER, HA A, 44, ALA, O 3.40Å
A, 41, ALA, HA B, 40, ASN, O 3.47Å
A, 45, SER, HA B, 44, ALA, O 3.40Å