UniProt data
UniProt name: PCD19_HUMAN (Q8TAB3)
Gene name: PCDH19; Synonyms=KIAA1313
Organism: Homo sapiens (Human).
Function: Potential calcium-dependent cell-adhesion protein.
Subcellular location: Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Transmembrane domains:
- 679-699, 21 AA, Helical. {ECO:0000255}.
Sequence: 1148 AA
10 20 30 40 50 60
MESLLLPVLL LLAILWTQAA ALINLKYSVE EEQRAGTVIA NVAKDAREAG FALDPRQASA
70 80 90 100 110 120
FRVVSNSAPH LVDINPSSGL LVTKQKIDRD LLCRQSPKCI ISLEVMSSSM EICVIKVEIK
130 140 150 160 170 180
DLNDNAPSFP AAQIELEISE AASPGTRIPL DSAYDPDSGS FGVQTYELTP NELFGLEIKT
190 200 210 220 230 240
RGDGSRFAEL VVEKSLDRET QSHYSFRITA LDGGDPPRLG TVGLSIKVTD SNDNNPVFSE
250 260 270 280 290 300
STYAVSVPEN SPPNTPVIRL NASDPDEGTN GQVVYSFYGY VNDRTRELFQ IDPHSGLVTV
310 320 330 340 350 360
TGALDYEEGH VYELDVQAKD LGPNSIPAHC KVTVSVLDTN DNPPVINLLS VNSELVEVSE
370 380 390 400 410 420
SAPPGYVIAL VRVSDRDSGL NGRVQCRLLG NVPFRLQEYE SFSTILVDGR LDREQHDQYN
430 440 450 460 470 480
LTIQARDGGV PMLQSAKSFT VLITDENDNH PHFSKPYYQV IVQENNTPGA YLLSVSARDP
490 500 510 520 530 540
DLGLNGSVSY QIVPSQVRDM PVFTYVSINP NSGDIYALRS FNHEQTKAFE FKVLAKDGGL
550 560 570 580 590 600
PSLQSNATVR VIILDVNDNT PVITAPPLIN GTAEVYIPRN SGIGYLVTVV KAEDYDEGEN
610 620 630 640 650 660
GRVTYDMTEG DRGFFEIDQV NGEVRTTRTF GESSKSSYEL IVVAHDHGKT SLSASALVLI
670 680 690 700 710 720
YLSPALDAQE SMGSVNLSLI FIIALGSIAG ILFVTMIFVA IKCKRDNKEI RTYNCSNCLT
730 740 750 760 770 780
ITCLLGCFIK GQNSKCLHCI SVSPISEEQD KKTEEKVSLR GKRIAEYSYG HQKKSSKKKK
790 800 810 820 830 840
ISKNDIRLVP RDVEETDKMN VVSCSSLTSS LNYFDYHQQT LPLGCRRSES TFLNVENQNT
850 860 870 880 890 900
RNTSANHIYH HSFNSQGPQQ PDLIINGVPL PETENYSFDS NYVNSRAHLI KSSSTFKDLE
910 920 930 940 950 960
GNSLKDSGHE ESDQTDSEHD VQRSLYCDTA VNDVLNTSVT SMGSQMPDHD QNEGFHCREE
970 980 990 1000 1010 1020
CRILGHSDRC WMPRNPMPIR SKSPEHVRNI IALSIEATAA DVEAYDDCGP TKRTFATFGK
1030 1040 1050 1060 1070 1080
DVSDHPAEER PTLKGKRTVD VTICSPKVNS VIREAGNGCE AISPVTSPLH LKSSLPTKPS
1090 1100 1110 1120 1130 1140
VSYTIALAPP ARDLEQYVNN VNNGPTRPSE AEPRGADSEK VMHEVSPILK EGRNKESPGV
KRLKDIVL
CATM prediction
The sequence of PCD19_HUMAN returned 1 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 680 690 700 | + | + | |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | NLSLIFIIALGSIAGILFVTMIFVAIK | 6.4 | -55.3° | 5.0 | 53.1 | -42.8 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 686, GLY, HA1 | A, 683, ILE, O | 3.07Å |
| B, 687, SER, HA | A, 686, GLY, O | 2.46Å |
| B, 690, GLY, HA1 | A, 687, SER, O | 3.11Å |
| A, 686, GLY, HA1 | B, 683, ILE, O | 3.07Å |
| A, 687, SER, HA | B, 686, GLY, O | 2.46Å |
| A, 690, GLY, HA1 | B, 687, SER, O | 3.11Å |