UniProt data
UniProt name: CS018_HUMAN (Q8NEA5)
Gene name: C19orf18
Organism: Homo sapiens (Human).
Function:
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Transmembrane domains:
- 101-121, 21 AA, Helical. {ECO:0000255}.
Sequence: 215 AA
10 20 30 40 50 60
MDKVQSGFLI LFLFLMECQL HLCLPYADGL HPTGNITGLP GSKRSQPPRN ITKEPKVFFH
70 80 90 100 110 120
KTQLPGIQGA ASRSTAASPT NPMKFLRNKA IIRHRPALVK VILISSVAFS IALICGMAIS
130 140 150 160 170 180
YMIYRLAQAE ERQQLESLYK NLRIPLLGDE EEGSEDEGES THLLPENENE LEKFIHSVII
190 200 210
SKRSKNIKKK LKEEQNSVTE NKTKNASHNG KMEDL
CATM prediction
The sequence of CS018_HUMAN returned 2 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 100 110 120 | + | + | |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | LVKVILISSVAFSIALICGMAISYMIY | 7.1 | -55.0° | 2.4 | 48.0 | -37.6 |
| Model 2 | LVKVILISSVAFSIALICGMAISYMIY | 7.3 | -40.1° | 4.5 | 44.0 | -10.3 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 113, LEU, HA | A, 112, ALA, O | 3.31Å |
| B, 116, GLY, HA1 | A, 113, LEU, O | 3.07Å |
| A, 113, LEU, HA | B, 112, ALA, O | 3.31Å |
| A, 116, GLY, HA1 | B, 113, LEU, O | 3.07Å |
| A, 117, MET, HA | B, 120, SER, OG | 3.25Å |
| A, 120, SER, HG1 | B, 120, SER, OG | 1.83Å |
