LRRN4 C-terminal-like protein

UniProt data

UniProt name: LRN4L_HUMAN (Q8ND94)

Gene name: LRRN4CL; ORFNames=UNQ728/PRO1410

Organism: Homo sapiens (Human).

Function:

Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.

Transmembrane domains:

  1. 195-215, 21 AA, Helical. {ECO:0000255}.

Sequence: 238 AA

10 20 30 40 50 60 MLGSPCLLWL LAVTFLVPRA QPLAPQDFEE EEADETETAW PPLPAVPCDY DHCRHLQVPC 70 80 90 100 110 120 KELQRVGPAA CLCPGLSSPA QPPDPPRMGE VRIAAEEGRA VVHWCAPFSP VLHYWLLLWD 130 140 150 160 170 180 GSEAAQKGPP LNATVRRAEL KGLKPGGIYV VCVVAANEAG ASRVPQAGGE GLEGADIPAF 190 200 210 220 230 GPCSRLAVPP NPRTLVHAAV GVGTALALLS CAALVWHFCL RDRWGCPRRA AARAAGAL

CATM prediction

The sequence of LRN4L_HUMAN returned 3 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
          200       210      
   +    |    +    |    +   		 (Å) (°) (Å) (°)  
Model 1 ARTLVHAAVGVGTALALLSCAALVWHF 7.0 -54.9° 2.4 48.1 -27.7
Model 2 ARTLVHAAVGVGTALALLSCAALVWHF 6.9 -46.0° 2.7 47.2 -18.5
Model 3 ARTLVHAAVGVGTALALLSCAALVWHF 7.2 -34.2° 5.7 34.2 -6.9
Prolines* PRTLVHAAVGVGTALALLSCAALVWHF          

* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


Click on the image to enlarge

Download model 1 structure: PDB, PyMOL session

List of hydrogen bonds:

Donor Acceptor Distance
B, 198, ALA, HA A, 197, HSE, O 3.49Å
B, 201, GLY, HA1 A, 198, ALA, O 3.02Å
A, 198, ALA, HA B, 197, HSE, O 3.49Å
A, 201, GLY, HA1 B, 198, ALA, O 3.02Å