Poly(A)-specific ribonuclease PARN-like domain-containing protein 1

UniProt data

UniProt name: PNDC1_HUMAN (Q8NA58)

Gene name: PNLDC1

Organism: Homo sapiens (Human).

Function:

Subcellular location: Membrane {ECO:0000305}; Single-pass type IV membrane protein {ECO:0000305}.

Transmembrane domains:

  1. 495-515, 21 AA, Helical; Anchor for type IV membrane protein. {ECO:0000255}.

Sequence: 520 AA

10 20 30 40 50 60 MFCTRGLLFF AFLAGLDIEF TGLRSNLSGP QQISLFDLPS EWYLKTRQSV QQFTVCQIGL 70 80 90 100 110 120 SVFSAIEGEA NKYIAHSCNF YLFPTTFGIL DSEFSFQASS VQFLNQYGFN YNKFLKNGIP 130 140 150 160 170 180 YMNEEQEKKI RHDILTGNWR VRSSPDKDQI KVVIDEVTRW LELAKEGDWM TLPGITGFQA 190 200 210 220 230 240 FEVQLVLRQA LPNIWTVLKD EGVVVKKVSK QHRWYLQNTS CDRESCWKEN ILLSARGFSV 250 260 270 280 290 300 FFQMLVKAQK PLVGHNMMMD LLHLHEKFFR PLPESYDQFK QNIHSLFPVL IDTKSVTKDI 310 320 330 340 350 360 WKEMNFPRVS NLSEVYEVLN SDLNPTKNSG PEIVHASRCE KYVETKCPHE AAYDAFLCGS 370 380 390 400 410 420 VLLKVAHLLL QKIYHIDPVP ESSFPQYLDV LAPYVNQVNL IRAGVPKINF SGPDYPSIRP 430 440 450 460 470 480 PILILSVKRW PGVSEQQVYH KFQNLCKFDV RRLTRSQFLL LTNKFKDARN ILKEYRDHPT 490 500 510 LCISLYRYWR HSPNVNCLLQ VCGIVTAWAL LAFILGRSGT

CATM prediction

The sequence of PNDC1_HUMAN returned 1 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
          500       510      
   +    |    +    |    +   		 (Å) (°) (Å) (°)  
Model 1 SANVNCLLQVCGIVTAWALLAFILGRS 7.3 -51.0° 2.4 44.8 -3.1
Prolines* SPNVNCLLQVCGIVTAWALLAFILGRS          

* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


Click on the image to enlarge

Download model 1 structure: PDB, PyMOL session

List of hydrogen bonds:

Donor Acceptor Distance
B, 500, GLN, HA A, 499, LEU, O 3.40Å
B, 503, GLY, HA1 A, 500, GLN, O 3.20Å
A, 500, GLN, HA B, 499, LEU, O 3.40Å
A, 503, GLY, HA1 B, 500, GLN, O 3.20Å