UniProt data
UniProt name: LRTM2_HUMAN (Q8N967)
Gene name: LRTM2
Organism: Homo sapiens (Human).
Function:
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Transmembrane domains:
- 311-331, 21 AA, Helical. {ECO:0000255}.
Sequence: 370 AA
10 20 30 40 50 60
MLAPGSSPGQ RGRLALQWRQ VSWITCWIAL YAVEALPTCP FSCKCDSRSL EVDCSGLGLT
70 80 90 100 110 120
TVPPDVPAAT RTLLLLNNKL SALPSWAFAN LSSLQRLDLS NNFLDRLPRS IFGDLTNLTE
130 140 150 160 170 180
LQLRNNSIRT LDRDLLRHSP LLRHLDLSIN GLAQLPPGLF DGLLALRSLS LRSNRLQNLD
190 200 210 220 230 240
RLTFEPLANL QLLQVGDNPW ECDCNLREFK HWMEWFSYRG GRLDQLACTL PKELRGKDMR
250 260 270 280 290 300
MVPMEMFNYC SQLEDENSSA GLDIPGPPCT KASPEPAKPK PGAEPEPEPS TACPQKQRHR
310 320 330 340 350 360
PASVRRAMGT VIIAGVVCGV VCIMMVVAAA YGCIYASLMA KYHRELKKRQ PLMGDPEGEH
EDQKQISSVA
CATM prediction
The sequence of LRTM2_HUMAN returned 2 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 310 320 330 | + | + | |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | MGTVIIAGVVCGVVCIMMVVAAAYGCI | 6.7 | -53.2° | 5.2 | 58.3 | -17.3 |
| Model 2 | MGTVIIAGVVCGVVCIMMVVAAAYGCI | 6.9 | -43.0° | 0.0 | 34.0 | -16.4 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 315, GLY, HA1 | A, 312, ILE, O | 3.32Å |
| B, 316, VAL, HA | A, 315, GLY, O | 2.81Å |
| A, 315, GLY, HA1 | B, 312, ILE, O | 3.32Å |
| A, 316, VAL, HA | B, 315, GLY, O | 2.81Å |
