UniProt data
UniProt name: SERP2_HUMAN (Q8N6R1)
Gene name: SERP2; Synonyms=C13orf21
Organism: Homo sapiens (Human).
Function: May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation (Potential). {ECO:0000305}.
Subcellular location: Membrane; Single-pass type IV membrane protein. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
Transmembrane domains:
- 38-58, 21 AA, Helical; Anchor for type IV membrane protein. {ECO:0000255}.
Sequence: 65 AA
CATM prediction
The sequence of SERP2_HUMAN returned 1 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 40 50 60 + | + | + | |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | YAVGAWLLALFVFVVCGSAIFQIIQSI | 7.1 | -52.9° | 2.0 | 44.8 | -23.5 |
| Prolines* | YPVGPWLLALFVFVVCGSAIFQIIQSI |
* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 48, VAL, HA | A, 47, PHE, O | 3.44Å |
| B, 51, GLY, HA1 | A, 48, VAL, O | 3.07Å |
| A, 48, VAL, HA | B, 47, PHE, O | 3.44Å |
| A, 51, GLY, HA1 | B, 48, VAL, O | 3.07Å |