Fibrinogen C domain-containing protein 1

UniProt data

UniProt name: FBCD1_HUMAN (Q8N539)

Gene name: FIBCD1; ORFNames=UNQ701/PRO1346

Organism: Homo sapiens (Human).

Function: Acetyl group-binding receptor which shows a high- affinity and calcium-dependent binding to acetylated structures such as chitin, some N-acetylated carbohydrates, and amino acids, but not to their non-acetylated counterparts. Can facilitate the endocytosis of acetylated components. {ECO:0000269|PubMed:19710473, ECO:0000269|PubMed:19892701}.

Subcellular location: Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.

Transmembrane domains:

  1. 34-54, 21 AA, Helical; Signal-anchor for type II membrane protein. {ECO:0000255}.

Sequence: 461 AA

10 20 30 40 50 60 MVNDRWKTMG GAAQLEDRPR DKPQRPSCGY VLCTVLLALA VLLAVAVTGA VLFLNHAHAP 70 80 90 100 110 120 GTAPPPVVST GAASANSALV TVERADSSHL SILIDPRCPD LTDSFARLES AQASVLQALT 130 140 150 160 170 180 EHQAQPRLVG DQEQELLDTL ADQLPRLLAR ASELQTECMG LRKGHGTLGQ GLSALQSEQG 190 200 210 220 230 240 RLIQLLSESQ GHMAHLVNSV SDILDALQRD RGLGRPRNKA DLQRAPARGT RPRGCATGSR 250 260 270 280 290 300 PRDCLDVLLS GQQDDGVYSV FPTHYPAGFQ VYCDMRTDGG GWTVFQRRED GSVNFFRGWD 310 320 330 340 350 360 AYRDGFGRLT GEHWLGLKRI HALTTQAAYE LHVDLEDFEN GTAYARYGSF GVGLFSVDPE 370 380 390 400 410 420 EDGYPLTVAD YSGTAGDSLL KHSGMRFTTK DRDSDHSENN CAAFYRGAWW YRNCHTSNLN 430 440 450 460 GQYLRGAHAS YADGVEWSSW TGWQYSLKFS EMKIRPVRED R

CATM prediction

The sequence of FBCD1_HUMAN returned 1 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
           40        50      
    +    |    +    |    +  		 (Å) (°) (Å) (°)  
Model 1 VLCTVLLALAVLLAVAVTGAVLFLNHA 6.9 -54.0° 2.6 32.9 -10.9

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


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Download model 1 structure: PDB, PyMOL session

List of hydrogen bonds:

Donor Acceptor Distance
B, 46, ALA, HA A, 45, VAL, O 3.25Å
B, 49, GLY, HA1 A, 46, ALA, O 2.94Å
A, 46, ALA, HA B, 45, VAL, O 3.25Å
A, 49, GLY, HA1 B, 46, ALA, O 2.94Å