Transmembrane protein 130

UniProt data

UniProt name: TM130_HUMAN (Q8N3G9)

Gene name: TMEM130; ORFNames=UNQ719/PRO1383

Organism: Homo sapiens (Human).

Function:

Subcellular location: Golgi apparatus membrane {ECO:0000269|PubMed:11256614}; Single-pass type I membrane protein {ECO:0000269|PubMed:11256614}.

Transmembrane domains:

  1. 340-360, 21 AA, Helical. {ECO:0000255}.

Sequence: 435 AA

10 20 30 40 50 60 MAQAVWSRLG RILWLACLLP WAPAGVAAGL YELNLTTDSP ATTGAVVTIS ASLVAKDNGS 70 80 90 100 110 120 LALPADAHLY RFHWIHTPLV LTGKMEKGLS STIRVVGHVP GEFPVSVWVT AADCWMCQPV 130 140 150 160 170 180 ARGFVVLPIT EFLVGDLVVT QNTSLPWPSS YLTKTVLKVS FLLHDPSNFL KTALFLYSWD 190 200 210 220 230 240 FGDGTQMVTE DSVVYYNYSI IGTFTVKLKV VAEWEEVEPD ATRAVKQKTG DFSASLKLQE 250 260 270 280 290 300 TLRGIQVLGP TLIQTFQKMT VTLNFLGSPP LTVCWRLKPE CLPLEEGECH PVSVASTAYN 310 320 330 340 350 360 LTHTFRDPGD YCFSIRAENI ISKTHQYHKI QVWPSRIQPA VFAFPCATLI TVMLAFIMYM 370 380 390 400 410 420 TLRNATQQKD MVEVADFDFS PMSDKNPEPP SGVRCCCQMC CGPFLLETPS EYLEIVRENH 430 GLLPPLYKSV KTYTV

CATM prediction

The sequence of TM130_HUMAN returned 1 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
     340       350       360 
   |    +    |    +    |   		 (Å) (°) (Å) (°)  
Model 1 IQAAVFAFACATLITVMLAFIMYMTLR 7.2 -37.0° 2.2 36.0 -0.4
Prolines* IQPAVFAFPCATLITVMLAFIMYMTLR          

* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


Click on the image to enlarge

Download model 1 structure: PDB, PyMOL session

List of hydrogen bonds:

Donor Acceptor Distance
B, 344, PHE, HA A, 343, ALA, O 3.36Å
A, 344, PHE, HA B, 343, ALA, O 3.36Å