UniProt data
UniProt name: VSI10_HUMAN (Q8N0Z9)
Gene name: VSIG10
Organism: Homo sapiens (Human).
Function:
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Transmembrane domains:
- 414-434, 21 AA, Helical. {ECO:0000255}.
Sequence: 540 AA
10 20 30 40 50 60
MAAGGSAPEP RVLVCLGALL AGWVAVGLEA VVIGEVHENV TLHCGNISGL RGQVTWYRNN
70 80 90 100 110 120
SEPVFLLSSN SSLRPAEPRF SLVDATSLHI ESLSLGDEGI YTCQEILNVT QWFQVWLQVA
130 140 150 160 170 180
SGPYQIEVHI VATGTLPNGT LYAARGSQVD FSCNSSSRPP PVVEWWFQAL NSSSESFGHN
190 200 210 220 230 240
LTVNFFSLLL ISPNLQGNYT CLALNQLSKR HRKVTTELLV YYPPPSAPQC WAQMASGSFM
250 260 270 280 290 300
LQLTCRWDGG YPDPDFLWIE EPGGVIVGKS KLGVEMLSES QLSDGKKFKC VTSHIVGPES
310 320 330 340 350 360
GASCMVQIRG PSLLSEPMKT CFTGGNVTLT CQVSGAYPPA KILWLRNLTQ PEVIIQPSSR
370 380 390 400 410 420
HLITQDGQNS TLTIHNCSQD LDEGYYICRA DSPVGVREME IWLSVKEPLN IGGIVGTIVS
430 440 450 460 470 480
LLLLGLAIIS GLLLHYSPVF CWKVGNTSRG QNMDDVMVLV DSEEEEEEEE EEEEDAAVGE
490 500 510 520 530
QEGAREREEL PKEIPKQDHI HRVTALVNGN IEQMGNGFQD LQDDSSEEQS DIVQEEDRPV
CATM prediction
The sequence of VSI10_HUMAN returned 2 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 420 430 + | + | + |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | IGGIVGTIVSLLLLGLAIISGLLLHYS | 7.2 | -51.2° | 3.3 | 48.0 | -24.1 |
| Model 2 | IGGIVGTIVSLLLLGLAIISGLLLHYS | 6.7 | -45.0° | 5.5 | 45.0 | -11.0 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 428, ILE, HA | A, 427, ALA, O | 3.26Å |
| B, 431, GLY, HA1 | A, 428, ILE, O | 3.26Å |
| A, 428, ILE, HA | B, 427, ALA, O | 3.26Å |
| A, 431, GLY, HA1 | B, 428, ILE, O | 3.26Å |
