Transmembrane protein 183A

UniProt data

UniProt name: T183A_HUMAN (Q8IXX5)

Gene name: TMEM183A; Synonyms=C1orf37

Organism: Homo sapiens (Human).

Function:

Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.

Transmembrane domains:

  1. 300-320, 21 AA, Helical. {ECO:0000255}.

Sequence: 376 AA

10 20 30 40 50 60 MARGPGPLGR PRPDTVAMPK RGKRLKFRAH DACSGRVTVA DYANSDPAVV RSGRVKKAVA 70 80 90 100 110 120 NAVQQEVKSL CGLEASQVPA EEALSGAGEP CDIIDSSDEM DAQEESIHER TVSRKKKSKR 130 140 150 160 170 180 HKEELDGAGG EEYPMDIWLL LASYIRPEDI VNFSLICKNA WTVTCTAAFW TRLYRRHYTL 190 200 210 220 230 240 DASLPLRLRP ESMEKLRCLR ACVIRSLYHM YEPFAARISK NPAIPESTPS TLKNSKCLLF 250 260 270 280 290 300 WCRKIVGNRQ EPMWEFNFKF KKQSPRLKSK CTGGLQPPVQ YEDVHTNPDQ DCCLLQVTTL 310 320 330 340 350 360 NFIFIPIVMG MIFTLFTINV STDMRHHRVR LVFQDSPVHG GRKLRSEQGV QVILDPVHSV 370 RLFDWWHPQY PFSLRA

CATM prediction

The sequence of T183A_HUMAN returned 1 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
     300       310       320 
   |    +    |    +    |   		 (Å) (°) (Å) (°)  
Model 1 VTTLNFIFIAIVMGMIFTLFTINVSTD 7.1 -46.1° 2.7 47.0 -18.4
Prolines* VTTLNFIFIPIVMGMIFTLFTINVSTD          

* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


Click on the image to enlarge

Download model 1 structure: PDB, PyMOL session

List of hydrogen bonds:

Donor Acceptor Distance
B, 307, ILE, HA A, 306, ALA, O 3.09Å
B, 310, GLY, HA1 A, 307, ILE, O 3.08Å
B, 311, MET, HA A, 314, THR, OG1 2.40Å
A, 307, ILE, HA B, 306, ALA, O 3.09Å
A, 310, GLY, HA1 B, 307, ILE, O 3.08Å
A, 311, MET, HA B, 314, THR, OG1 2.50Å