Type III endosome membrane protein TEMP {ECO:0000250|UniProtKB:Q9CQM1}

UniProt data

UniProt name: CA210_HUMAN (Q8IVY1)

Gene name: C1orf210

Organism: Homo sapiens (Human).

Function: May be involved in membrane trafficking between endosomes and plasma membrane.

Subcellular location: Membrane {ECO:0000305}; Single-pass type III membrane protein {ECO:0000305}. Early endosome {ECO:0000250|UniProtKB:Q9CQM1}. Recycling endosome {ECO:0000250|UniProtKB:Q9CQM1}. Cell membrane {ECO:0000250|UniProtKB:Q9CQM1}. Note=Also localizes to tubular endosome structures. {ECO:0000250|UniProtKB:Q9CQM1}.

Transmembrane domains:

  1. 30-50, 21 AA, Helical; Signal-anchor for type III membrane protein. {ECO:0000255}.

Sequence: 113 AA

10 20 30 40 50 60 MNETNKTLVG PSELPTASAV APGPGTGARA WPVLVGFVLG AVVLSLLIAL AAKCHLCRRY 70 80 90 100 110 HASYRHRPLP ETGRGGRPQV AEDEDDDGFI EDNYIQPGTG ELGTEGSRDH FSL

CATM prediction

The sequence of CA210_HUMAN returned 1 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
     30        40        50  
   |    +    |    +    |   		 (Å) (°) (Å) (°)  
Model 1 GARAWAVLVGFVLGAVVLSLLIALAAK 7.2 -42.9° 3.4 50.1 -20.3
Prolines* GARAWPVLVGFVLGAVVLSLLIALAAK          

* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


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Download model 1 structure: PDB, PyMOL session

List of hydrogen bonds:

Donor Acceptor Distance
B, 33, VAL, HA A, 32, ALA, O 3.06Å
B, 36, GLY, HA1 A, 33, VAL, O 3.28Å
A, 33, VAL, HA B, 32, ALA, O 3.06Å
A, 36, GLY, HA1 B, 33, VAL, O 3.28Å