UniProt data
UniProt name: IGDC3_HUMAN (Q8IVU1)
Gene name: IGDCC3; Synonyms=PUNC
Organism: Homo sapiens (Human).
Function:
Subcellular location: Membrane; Single-pass type I membrane protein.
Transmembrane domains:
- 641-661, 21 AA, Helical. {ECO:0000255}.
Sequence: 814 AA
10 20 30 40 50 60
MAVQRAASPR RPPAPLWPRL LLPLLLLLLP APSEGLGHSA ELAFAVEPSD DVAVPGQPIV
70 80 90 100 110 120
LDCRVEGTPP VRITWRKNGV ELPESTHSTL LANGSLMIRH FRLEPGGSPS DEGDYECVAQ
130 140 150 160 170 180
NRFGLVVSRK ARIQAATMSD FHVHPQATVG EEGGVARFQC QIHGLPKPLI TWEKNRVPID
190 200 210 220 230 240
TDNERYTLLP KGVLQITGLR AEDGGIFHCV ASNIASIRIS HGARLTVSGS GSGAYKEPAI
250 260 270 280 290 300
LVGPENLTLT VHQTAVLECV ATGNPRPIVS WSRLDGRPIG VEGIQVLGTG NLIISDVTVQ
310 320 330 340 350 360
HSGVYVCAAN RPGTRVRRTA QGRLVVQAPA EFVQHPQSIS RPAGTTAMFT CQAQGEPPPH
370 380 390 400 410 420
VTWLKNGQVL GPGGHVRLKN NNSTLTISGI GPEDEAIYQC VAENSAGSSQ ASARLTVLWA
430 440 450 460 470 480
EGLPGPPRNV RAVSVSSTEV RVSWSEPLAN TKEIIGYVLH IRKAADPPEL EYQEAVSKST
490 500 510 520 530 540
FQHLVSDLEP STAYSFYIKA YTPRGASSAS VPTLASTLGE APAPPPLSVR VLGSSSLQLL
550 560 570 580 590 600
WEPWPRLAQH EGGFKLFYRP ASKTSFTGPI LLPGTVSSYN LSQLDPTAVY EVKLLAYNQH
610 620 630 640 650 660
GDGNATVRFV SLRGASERTA LSPPCDCRKE EAANQTSTTG IVIGIHIGVT CIIFCVLFLL
670 680 690 700 710 720
FGQRGRVLLC KDVENQLSPP QGPRSQRDPG ILALNGARRG QRGQLGRDEK RVDMKELEQL
730 740 750 760 770 780
FPPASAAGQP DPRPTQDPAA PAPCEETQLS VLPLQGCGLM EGKTTEAKTT EATAPCAGLA
790 800 810
AAPPPPDGGP GLLSEGQASR PAAARVTQPA HSEQ
CATM prediction
The sequence of IGDC3_HUMAN returned 3 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 640 650 660 | + | + | |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | TTGIVIGIHIGVTCIIFCVLFLLFGQR | 6.4 | -51.7° | 1.4 | 57.0 | -28.0 |
| Model 2 | TTGIVIGIHIGVTCIIFCVLFLLFGQR | 6.8 | -28.0° | 6.0 | 47.0 | -25.4 |
| Model 3 | TTGIVIGIHIGVTCIIFCVLFLLFGQR | 6.6 | -55.0° | 5.0 | 53.0 | -9.5 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 644, GLY, HA1 | A, 641, ILE, O | 2.55Å |
| B, 645, ILE, HA | A, 644, GLY, O | 2.95Å |
| A, 644, GLY, HA1 | B, 641, ILE, O | 2.55Å |
| A, 645, ILE, HA | B, 644, GLY, O | 2.95Å |
