AP20 region protein 1

UniProt data

UniProt name: APRG1_HUMAN (Q8IVJ8)

Gene name: APRG1; Synonyms=C3orf35

Organism: Homo sapiens (Human).

Function:

Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.

Transmembrane domains:

  1. 150-170, 21 AA, Helical. {ECO:0000255}.

Sequence: 170 AA

10 20 30 40 50 60 MKTMATRKRC KLSRTGPEFE NVIKRLLCAR TFHTRIGGDL THGIINRGRR ANAEQMGLQG 70 80 90 100 110 120 SAQHFNIFPL DLWTQGKKTE VQKREGTDSI PAAGRSGTAN QPSIAPHRCL FSRGITALDG 130 140 150 160 LKRGRGCNGA AHLVRGDAWK TKLGEPWVSI ALALAGPGAI LILELSWFLG

CATM prediction

The sequence of APRG1_HUMAN returned 1 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
     150       160       1
   |    +    |    +    |		 (Å) (°) (Å) (°)  
Model 1 WVSIALALAGAGAILILELSWFLG 7.4 -54.0° 3.6 35.5 -5.7
Prolines* WVSIALALAGPGAILILELSWFLG          

* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


Click on the image to enlarge

Download model 1 structure: PDB, PyMOL session

List of hydrogen bonds:

Donor Acceptor Distance
B, 155, ALA, HA A, 154, LEU, O 3.47Å
B, 158, GLY, HA1 A, 155, ALA, O 3.48Å
A, 155, ALA, HA B, 154, LEU, O 3.47Å
A, 158, GLY, HA1 B, 155, ALA, O 3.48Å