UniProt data
UniProt name: EPHX4_HUMAN (Q8IUS5)
Gene name: EPHX4; Synonyms=ABHD7, EPHXRP
Organism: Homo sapiens (Human).
Function:
Subcellular location: Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Transmembrane domains:
- 17-37, 21 AA, Helical; Signal-anchor for type II membrane protein. {ECO:0000255}.
Sequence: 362 AA
10 20 30 40 50 60
MARLRDCLPR LMLTLRSLLF WSLVYCYCGL CASIHLLKLL WSLGKGPAQT FRRPAREHPP
70 80 90 100 110 120
ACLSDPSLGT HCYVRIKDSG LRFHYVAAGE RGKPLMLLLH GFPEFWYSWR YQLREFKSEY
130 140 150 160 170 180
RVVALDLRGY GETDAPIHRQ NYKLDCLITD IKDILDSLGY SKCVLIGHDW GGMIAWLIAI
190 200 210 220 230 240
CYPEMVMKLI VINFPHPNVF TEYILRHPAQ LLKSSYYYFF QIPWFPEFMF SINDFKVLKH
250 260 270 280 290 300
LFTSHSTGIG RKGCQLTTED LEAYIYVFSQ PGALSGPINH YRNIFSCLPL KHHMVTTPTL
310 320 330 340 350 360
LLWGENDAFM EVEMAEVTKI YVKNYFRLTI LSEASHWLQQ DQPDIVNKLI WTFLKEETRK
KD
CATM prediction
The sequence of EPHX4_HUMAN returned 1 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 20 30 4 + | + | + | |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | TLRSLLFWSLVYCYCGLCASIHLLKLL | 7.3 | -55.1° | 2.4 | 48.0 | -25.5 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 26, CYS, HA | A, 25, TYR, O | 3.45Å |
| B, 29, GLY, HA1 | A, 26, CYS, O | 3.20Å |
| B, 30, LEU, HA | A, 33, SER, OG | 3.33Å |
| B, 33, SER, HG1 | A, 33, SER, OG | 1.88Å |
| A, 26, CYS, HA | B, 25, TYR, O | 3.45Å |
| A, 29, GLY, HA1 | B, 26, CYS, O | 3.20Å |