UniProt data
UniProt name: PLDX1_HUMAN (Q8IUK5)
Gene name: PLXDC1; Synonyms=TEM3, TEM7
Organism: Homo sapiens (Human).
Function: Plays a critical role in endothelial cell capillary morphogenesis. {ECO:0000250}.
Subcellular location: Isoform 4: Cytoplasm {ECO:0000305}.
Transmembrane domains:
- 427-447, 21 AA, Helical. {ECO:0000255}.
Sequence: 500 AA
10 20 30 40 50 60
MRGELWLLVL VLREAARALS PQPGAGHDEG PGSGWAAKGT VRGWNRRARE SPGHVSEPDR
70 80 90 100 110 120
TQLSQDLGGG TLAMDTLPDN RTRVVEDNHS YYVSRLYGPS EPHSRELWVD VAEANRSQVK
130 140 150 160 170 180
IHTILSNTHR QASRVVLSFD FPFYGHPLRQ ITIATGGFIF MGDVIHRMLT ATQYVAPLMA
190 200 210 220 230 240
NFNPGYSDNS TVVYFDNGTV FVVQWDHVYL QGWEDKGSFT FQAALHHDGR IVFAYKEIPM
250 260 270 280 290 300
SVPEISSSQH PVKTGLSDAF MILNPSPDVP ESRRRSIFEY HRIELDPSKV TSMSAVEFTP
310 320 330 340 350 360
LPTCLQHRSC DACMSSDLTF NCSWCHVLQR CSSGFDRYRQ EWMDYGCAQE AEGRMCEDFQ
370 380 390 400 410 420
DEDHDSASPD TSFSPYDGDL TTTSSSLFID SLTTEDDTKL NPYAGGDGLQ NNLSPKTKGT
430 440 450 460 470 480
PVHLGTIVGI VLAVLLVAAI ILAGIYINGH PTSNAALFFI ERRPHHWPAM KFRSHPDHST
490
YAEVEPSGHE KEGFMEAEQC
CATM prediction
The sequence of PLDX1_HUMAN returned 3 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 430 440 4 + | + | + | |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | LGTIVGIVLAVLLVAAIILAGIYINGH | 7.0 | -43.0° | 2.4 | 44.0 | -20.2 |
| Model 2 | LGTIVGIVLAVLLVAAIILAGIYINGH | 6.3 | -54.0° | 3.0 | 62.0 | -7.8 |
| Model 3 | LGTIVGIVLAVLLVAAIILAGIYINGH | 7.0 | -55.0° | 0.9 | 49.7 | -7.5 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 430, ILE, HA | A, 429, GLY, O | 3.39Å |
| A, 430, ILE, HA | B, 429, GLY, O | 3.39Å |
