UniProt data
UniProt name: VS10L_HUMAN (Q86VR7)
Gene name: VSIG10L
Organism: Homo sapiens (Human).
Function:
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Transmembrane domains:
- 777-797, 21 AA, Helical. {ECO:0000255}.
Sequence: 867 AA
10 20 30 40 50 60
MDNPQALPLF LLLASLVGIL TLRASSGLQQ TNFSSAFSSD SKSSSQGLGV EVPSIKPPSW
70 80 90 100 110 120
KVPDQFLDSK ASAGISDSSW FPEALSSNMS GSFWSNVSAE GQDLSPVSPF SETPGSEVFP
130 140 150 160 170 180
DISDPQVPAK DPKPSFTVKT PASNISTQVS HTKLSVEAPD SKFSPDDMDL KLSAQSPESK
190 200 210 220 230 240
FSAETHSAAS FPQQVGGPLA VLVGTTIRLP LVPIPNPGPP TSLVVWRRGS KVLAAGGLGP
250 260 270 280 290 300
GAPLISLDPA HRDHLRFDQA RGVLELASAQ LDDAGVYTAE VIRAGVSQQT HEFTVGVYEP
310 320 330 340 350 360
LPQLSVQPKA PETEEGAAEL RLRCLGWGPG RGELSWSRDG RALEAAESEG AETPRMRSEG
370 380 390 400 410 420
DQLLIVRPVR SDHARYTCRV RSPFGHREAA ADVSVFYGPD PPTITVSSDR DAAPARFVTA
430 440 450 460 470 480
GSNVTLRCAA ASRPPADITW SLADPAEAAV PAGSRLLLPA VGPGHAGTYA CLAANPRTGR
490 500 510 520 530 540
RRRSLLNLTV ADLPPGAPQC SVEGGPGDRS LRFRCSWPGG APAASLQFQG LPEGIRAGPV
550 560 570 580 590 600
SSVLLAAVPA HPRLSGVPIT CLARHLVATR TCTVTPEAPR EVLLHPLVAE TRLGEAEVAL
610 620 630 640 650 660
EASGCPPPSR ASWAREGRPL APGGGSRLRL SQDGRKLHIG NFSLDWDLGN YSVLCSGALG
670 680 690 700 710 720
AGGDQITLIG PSISSWRLQR ARDAAVLTWD VERGALISSF EIQAWPDGPA LGRTSTYRDW
730 740 750 760 770 780
VSLLILGPQE RSAVVPLPPR NPGTWTFRIL PILGGQPGTP SQSRVYRAGP TLSHGAIAGI
790 800 810 820 830 840
VLGSLLGLAL LAVLLLLCIC CLCRFRGKTP EKKKHPSTLV PVVTPSEKKM HSVTPVEISW
850 860
PLDLKVPLED HSSTRAYQAQ TPVQLSL
CATM prediction
The sequence of VS10L_HUMAN returned 6 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 780 790 8 + | + | + | |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | HGAIAGIVLGSLLGLALLAVLLLLCIC | 6.6 | -35.0° | 3.7 | 53.4 | -42.5 |
| Model 2 | HGAIAGIVLGSLLGLALLAVLLLLCIC | 6.5 | -30.0° | 3.5 | 53.0 | -31.4 |
| Model 3 | HGAIAGIVLGSLLGLALLAVLLLLCIC | 6.8 | -49.0° | 5.4 | 48.8 | -31.0 |
| Model 4 | HGAIAGIVLGSLLGLALLAVLLLLCIC | 6.3 | -45.0° | 2.7 | 61.0 | -23.2 |
| Model 5 | HGAIAGIVLGSLLGLALLAVLLLLCIC | 6.4 | -55.1° | 5.9 | 47.0 | -21.5 |
| Model 6 | HGAIAGIVLGSLLGLALLAVLLLLCIC | 6.6 | -54.0° | 4.8 | 41.0 | -11.9 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 780, ILE, HA | A, 779, GLY, O | 2.47Å |
| B, 783, GLY, HA1 | A, 780, ILE, O | 2.91Å |
| B, 784, SER, HA | A, 783, GLY, O | 3.25Å |
| A, 780, ILE, HA | B, 779, GLY, O | 2.47Å |
| A, 783, GLY, HA1 | B, 780, ILE, O | 2.91Å |
| A, 784, SER, HA | B, 783, GLY, O | 3.25Å |
