UniProt data
UniProt name: CEA19_HUMAN (Q7Z692)
Gene name: CEACAM19; Synonyms=CEAL1; ORFNames=UNQ2973/PRO7436
Organism: Homo sapiens (Human).
Function:
Subcellular location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Transmembrane domains:
- 158-178, 21 AA, Helical. {ECO:0000255}.
Sequence: 300 AA
10 20 30 40 50 60
MEIPMGTQGC FSKSLLLSAS ILVLWMLQGS QAALYIQKIP EQPQKNQDLL LSVQGVPDTF
70 80 90 100 110 120
QDFNWYLGEE TYGGTRLFTY IPGIQRPQRD GSAMGQRDIV GFPNGSMLLR RAQPTDSGTY
130 140 150 160 170 180
QVAITINSEW TMKAKTEVQV AEKNKELPST HLPTNAGILA ATIIGSLAAG ALLISCIAYL
190 200 210 220 230 240
LVTRNWRGQS HRLPAPRGQG SLSILCSAVS PVPSVTPSTW MATTEKPELG PAHDAGDNNI
250 260 270 280 290
YEVMPSPVLL VSPISDTRSI NPARPLPTPP HLQAEPENHQ YQQDLLNPDP APYCQLVPTS
CATM prediction
The sequence of CEA19_HUMAN returned 2 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 160 170 18 + | + | + | |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | NAGILAATIIGSLAAGALLISCIAYLL | 6.8 | -49.9° | 2.8 | 47.2 | -28.4 |
| Model 2 | NAGILAATIIGSLAAGALLISCIAYLL | 7.3 | -51.1° | 3.3 | 47.6 | -13.8 |
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 162, THR, HA | A, 161, ALA, O | 2.85Å |
| B, 165, GLY, HA1 | A, 162, THR, O | 2.78Å |
| A, 162, THR, HA | B, 161, ALA, O | 2.85Å |
| A, 165, GLY, HA1 | B, 162, THR, O | 2.78Å |
