UniProt data
UniProt name: LYSM3_HUMAN (Q7Z3D4)
Gene name: LYSMD3
Organism: Homo sapiens (Human).
Function:
Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Transmembrane domains:
- 218-238, 21 AA, Helical. {ECO:0000255}.
Sequence: 306 AA
10 20 30 40 50 60
MAGRHQNRSF PLPGVQSSGQ VHAFGNCSDS DILEEDAEVY ELRSRGKEKV RRSTSRDRLD
70 80 90 100 110 120
DIIVLTKDIQ EGDTLNAIAL QYCCTVADIK RVNNLISDQD FFALRSIKIP VKKFSSLTET
130 140 150 160 170 180
LCPPKGRQTS RHSSVQYSSE QQEILPANDS LAYSDSAGSF LKEVDRDIEQ IVKCTDNKRE
190 200 210 220 230 240
NLNEVVSALT AQQMRFEPDN KNTQRKDPYY GADWGIGWWT AVVIMLIVGI ITPVFYLLYY
250 260 270 280 290 300
EILAKVDVSH HSTVDSSHLH SKITPPSQQR EMENGIVPTK GIHFSQQDDH KLYSQDSQSP
AAQQET
CATM prediction
The sequence of LYSM3_HUMAN returned 1 potential models
The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.
| # | Sequence and interface | d | θ | Z' | ω' | Score |
|---|---|---|---|---|---|---|
| 220 230 24 + | + | + | |
(Å) | (°) | (Å) | (°) | ||
| Model 1 | GIGWWTAVVIMLIVGIITAVFYLLYYE | 7.1 | -54.9° | 2.4 | 48.2 | -26.1 |
| Prolines* | GIGWWTAVVIMLIVGIITPVFYLLYYE |
* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.
Click on the model number to visualize its details below.
MODEL 1 DETAILS
Precited structure:
Click on the image to enlarge
Download model 1 structure: PDB, PyMOL session
List of hydrogen bonds:
| Donor | Acceptor | Distance |
|---|---|---|
| B, 226, LEU, HA | A, 225, MET, O | 3.36Å |
| B, 229, GLY, HA1 | A, 226, LEU, O | 3.04Å |
| A, 226, LEU, HA | B, 225, MET, O | 3.36Å |
| A, 229, GLY, HA1 | B, 226, LEU, O | 3.04Å |