Small integral membrane protein 15

UniProt data

UniProt name: SIM15_HUMAN (Q7Z3B0)

Gene name: SMIM15; Synonyms=C5orf43

Organism: Homo sapiens (Human).

Function:

Subcellular location: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.

Transmembrane domains:

  1. 20-40, 21 AA, Helical. {ECO:0000255}.

Sequence: 74 AA

10 20 30 40 50 60 MFDIKAWAEY VVEWAAKDPY GFLTTVILAL TPLFLASAVL SWKLAKMIEA REKEQKKKQK 70 RQENIAKAKR LKKD

CATM prediction

The sequence of SIM15_HUMAN returned 1 potential models

The positions at the dimer's interface are highlighted in yellow. The position at the crossing point is highlighted in orange.

# Sequence and interface d θ Z' ω' Score
     20        30        40  
   |    +    |    +    |   
(Å) (°) (Å) (°)  
KDAYGFLTTVILALTALFLASAVLSWK 7.1 -40.0° 4.0 38.0 -4.0
KDPYGFLTTVILALTPLFLASAVLSWK          

* Note: this sequence contains Pro residues. CATM substituted them with Ala during the modeling. The positions are marked.

Click on the model number to visualize its details below.

MODEL 1 DETAILS

Precited structure:


Click on the image to enlarge

Download model 1 structure: PDB, PyMOL session

List of hydrogen bonds:

Donor Acceptor Distance
B, 22, PHE, HA A, 25, THR, OG1 2.55Å
A, 22, PHE, HA B, 25, THR, OG1 2.55Å